Effect of Different Filling Techniques on Healing in Lesional Teeth
Comparison of the Effect of Orthograde and Retrograde Mineral Trioxide Aggregate Application on Healing After Apical Resection in Teeth With Periapical Lesions
This study tests whether different ways of filling teeth can help people with apical cysts heal better after treatment.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | TC Erciyes University Academic / other |
| Locations | 1 site (Kayseri) |
| Trial ID | NCT06384014 on ClinicalTrials.gov |
What this trial studies
This clinical trial examines how various filling techniques impact the healing of teeth affected by apical cysts. It focuses on non-surgical endodontic treatment aimed at eliminating microorganisms from the root canal system and creating a barrier to prevent further infection. The study will compare retrograde and orthograde root canal filling methods to determine which is more effective in promoting healing in periapical lesions. Participants will undergo treatment and be monitored for healing outcomes.
Who should consider this trial
Good fit: Ideal candidates are healthy individuals aged 18 to 65 with single-rooted teeth exhibiting periapical lesions larger than 1 cm.
Not a fit: Patients with systemic diseases, severely damaged teeth, or contraindications for surgical procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve healing rates in patients with apical cysts, leading to better dental health outcomes.
How similar studies have performed: While there have been studies on various filling techniques, this specific approach focusing on apical cysts and comparing retrograde and orthograde methods is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy volunteers without systemic disease between the ages of 18 and 65 * Single-rooted teeth with periapical lesions larger than 1 cm * Patients who do not have any contraindications for the surgical procedure. Exclusion Criteria: * Individuals with systemic diseases and allergic reactions * Pregnancy and breastfeeding * Severely damaged teeth * Patients with contraindications for surgical operation
Where this trial is running
Kayseri
- Erciyes Üniversitesi Diş Hekimliği Fakültesi — Kayseri, Turkey (Recruiting)
Study contacts
- Principal investigator: Eraslan Akyüz — Baş Araştirmaci
- Study coordinator: Eraslan Akyüz
- Email: ipekemamak@hotmail.com
- Phone: 4447138
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.