Effect of Dexamethasone on Swelling and Trismus After Wisdom Tooth Extraction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the impact of dexamethasone submucosal injection on reducing swelling and trismus in adults undergoing the surgical extraction of lower impacted third molars. Participants will be randomly assigned to receive either dexamethasone or a placebo after surgery, with follow-up visits scheduled to assess outcomes. The study employs a double-blind methodology to ensure unbiased results, with measurements taken using standardized techniques to evaluate trismus and edema. The goal is to determine if dexamethasone can improve postoperative recovery compared to conventional treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with impacted lower third molars requiring surgical extraction.
* Adults over the age of 18 years old.
* American Society of Anaesthesiologists (ASA) 1, and ASA 2

Exclusion Criteria:

* Patients with preoperative intraoral or extraoral swelling.
* Patients requiring simple extraction (Class I group A according to Pell and ---Gregory classification).
* Patients with uncontrolled systemic disease such as uncontrolled diabetic - patients.
* Patients who are allergic to corticosteroids.
* Patients who are contraindicated to use corticosteroids such as uncontrolled diabetic patients, and osteoporotic patients.
* Patients who require extraction of additional teeth at the same visit.

Where it's running

• King Abdulaziz University, Faculty of Dentistry
  Jeddah, Mecca Region, Saudi Arabia Recruiting

Study contacts

• Study coordinator: Lojain Bassyoni, BDS, MSc, FRCDC
• Email: lbassyoni@kau.edu.sa
• Phone: 00966504623553

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.