Effect of Cervical Plexus Block on Stress Response During Spine Surgery
Effect of Bilateral Ultrasound-Guided Intermediate Cervical Plexus Block Combined With General Anesthesia on THE Stress Response in Patients Undergoing Anterior Cervical Spine Surgery. A Randomized Controlled Study
This study is testing if a special nerve block combined with general anesthesia can help reduce stress and inflammation in patients having cervical spine surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 66 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Giza, October) |
| Trial ID | NCT06064214 on ClinicalTrials.gov |
What this trial studies
This study investigates how a bilateral ultrasound-guided intermediate cervical plexus block, combined with general anesthesia, affects the stress and inflammatory responses in patients undergoing anterior cervical spine surgery. The research focuses on the hormonal and metabolic changes that occur due to surgical stress, particularly the rise in cortisol and proinflammatory cytokines like interleukin-6. By understanding these responses, the study aims to improve postoperative outcomes and reduce stress-related complications. The intervention is designed for patients classified as ASA I and II, aged 18 to 65, who are scheduled for specific cervical spine procedures.
Who should consider this trial
Good fit: Ideal candidates are ASA I and II patients aged 18 to 65 undergoing anterior cervical discectomy or fixation.
Not a fit: Patients who may not benefit include those with allergies to local anesthetics, infections at the puncture site, or those undergoing emergency surgeries.
Why it matters
Potential benefit: If successful, this approach could lead to reduced stress and inflammation in patients undergoing cervical spine surgery, potentially improving recovery outcomes.
How similar studies have performed: Other studies have shown promising results with similar approaches in managing surgical stress, indicating potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1. ASA I \& ASA II patients.(The American Society of Anesthesiologists) 2. Age group: from 18 to 65 years old. 3. Patients undergoing anterior cervical discectomy or fixation. 4. Genders eligible for study: both sexes Exclusion Criteria: * • Patient refusal. * Patient Undergoing posterior fixation in addition to anterior. * An allergy to local anaesthetics. * Infection at block puncture site. * Bleeding disorders (Coagulopathy: PTT(partial thromboplastin time) \> 40seconds, INR(international normalised ratio) \> 1.2, platelet count \< 120 x 103 / L.). * Emergency surgeries \& patients in sepsis
Where this trial is running
Giza, October
- Ahmed Raafat — Giza, October, Egypt (Recruiting)
Study contacts
- Principal investigator: gomaa zohry, professor — cairo universitey
- Study coordinator: ahmed raafat, master's
- Email: ahmedtaha840@hotmail.com
- Phone: 01278996596
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.