Effect of Capsinoid Supplementation on Brown Fat in Obese Teens
Study of the Effect of Capsinoid Supplementation on Brown Adipose Tissue in Obese Adolescents
This study is testing if taking capsinoid supplements can help obese teenagers activate their brown fat to manage their weight better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 38 (estimated) |
| Ages | 11 Years to 18 Years |
| Sex | All |
| Sponsor | University of Avignon Academic / other |
| Locations | 1 site (Palavas-les-Flots) |
| Trial ID | NCT06916208 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of capsinoid supplementation on the activation of brown adipose tissue (BAT) in obese adolescents. BAT is known for its role in regulating energy expenditure and combating obesity by converting energy into heat. The trial includes a control group receiving a placebo to compare the effects of the capsinoid intervention. Participants will be monitored for changes in body composition and metabolic activity associated with BAT activation. The study aims to explore new dietary strategies to enhance weight management in this population.
Who should consider this trial
Good fit: Ideal candidates for this study are adolescents aged 11 to 18 with a BMI Z score indicating stage 2 obesity.
Not a fit: Patients with known allergies to capsinoids or those with certain digestive health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a novel dietary approach to help obese adolescents manage their weight more effectively.
How similar studies have performed: While the activation of brown adipose tissue has been explored in other studies, the specific use of capsinoid supplementation in this demographic is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * member or beneficiary of a health insurance scheme * aged between 11 and 18 * Body Mass Index Z score corresponding to stage 2 obesity according to the curves of Rolland-Cachera et al., 1991 and an absence of weight loss of more than 5% of the total weight over the last 3 months. * effective contraception (in pubescent females) Exclusion Criteria: * known allergy to capsinoids and/or soya * inflammatory digestive pathology and/or history of digestive tract surgery * participation in another study or in a period of exclusion determined by a previous study * pregnant, parturient or breastfeeding * The holder(s) of parental authority or the adolescent refuse(s) to sign the authorisation or acceptance form, respectively. * It proves impossible to provide the adolescent or parental guardian(s) with informed information.
Where this trial is running
Palavas-les-Flots
- Institut Saint Pierre — Palavas-les-Flots, France (Recruiting)
Study contacts
- Study coordinator: Agnès VINET
- Email: agnes.vinet@univ-avignon.fr
- Phone: +33 4 13 95 13 44
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.