Effect of Capsinoid Supplementation on Brown Fat in Obese Teens

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of capsinoid supplementation on the activation of brown adipose tissue (BAT) in obese adolescents. BAT is known for its role in regulating energy expenditure and combating obesity by converting energy into heat. The trial includes a control group receiving a placebo to compare the effects of the capsinoid intervention. Participants will be monitored for changes in body composition and metabolic activity associated with BAT activation. The study aims to explore new dietary strategies to enhance weight management in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* member or beneficiary of a health insurance scheme
* aged between 11 and 18
* Body Mass Index Z score corresponding to stage 2 obesity according to the curves of Rolland-Cachera et al., 1991 and an absence of weight loss of more than 5% of the total weight over the last 3 months.
* effective contraception (in pubescent females)

Exclusion Criteria:

* known allergy to capsinoids and/or soya
* inflammatory digestive pathology and/or history of digestive tract surgery
* participation in another study or in a period of exclusion determined by a previous study
* pregnant, parturient or breastfeeding
* The holder(s) of parental authority or the adolescent refuse(s) to sign the authorisation or acceptance form, respectively.
* It proves impossible to provide the adolescent or parental guardian(s) with informed information.

Where it's running

• Institut Saint Pierre
  Palavas-les-Flots, France Recruiting

Study contacts

• Study coordinator: Agnès VINET
• Email: agnes.vinet@univ-avignon.fr
• Phone: +33 4 13 95 13 44

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.