Effect of brain stimulation on stress response in healthy individuals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of transcranial alternating current stimulation (tACS) at alpha frequency on the stress response in healthy individuals. Participants will undergo a standardized stress test while receiving tACS targeting the dorsolateral prefrontal cortex. The primary goal is to assess how this stimulation affects cortisol reactivity, a key indicator of stress response, as well as other relevant biological and neuropsychological parameters. The study aims to enhance understanding of the relationship between brain activity and stress management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Right-handed Men and Women aged between 18 and 45
* If woman, hormonal contraception required
* Having given their written informed consent
* Affiliated with a social security scheme
* French speakers and readers

Exclusion Criteria:

* Contraindication to the exposure to exposure to tACS
* Current psychiatric disorder as classified in the DSM-5
* Regular intake of any psychotropic drug or Beta Blocker
* Recent exposure to a traumatic event
* Any debilitating condition making the experimental procedure not feasible
* Pregnancy

Where it's running

• Centre Hospitalier Le Vinatier
  Bron, Aura, France Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.