Effect of brain stimulation on cognitive control
Causal Role of Delta and Theta Oscillations in Hierarchical Cognitive Control
This study is testing if a special type of brain stimulation can help healthy people improve their thinking and decision-making skills.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 35 Years |
| Sex | All |
| Sponsor | Florida State University Academic / other |
| Locations | 1 site (Tallahassee, Florida) |
| Trial ID | NCT06734377 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates how rhythmic transcranial magnetic stimulation (TMS) at delta and theta frequencies affects cognitive control in healthy individuals. The study involves two tasks designed to assess hierarchical cognitive control, where participants respond to stimuli based on memorized rules and feature comparisons. By modulating neural oscillations through targeted stimulation, the research aims to enhance cognitive performance and understand the underlying neural mechanisms involved in cognitive tasks.
Who should consider this trial
Good fit: Ideal candidates are healthy right-handed individuals aged 18 to 35 with normal or corrected-to-normal vision.
Not a fit: Patients with neurological disorders, a history of seizures, or those currently receiving treatment for ADHD/ADD may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to new non-invasive methods for enhancing cognitive performance in healthy individuals.
How similar studies have performed: Previous studies have shown that rhythmic TMS can effectively modulate neural oscillations, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants must be between the ages of 18 and 35. * Must be able to provide informed consent. * Must have normal or corrected-to-normal vision. * Participants must be right-handed. * Willingness to comply with all study procedures and availability for the study duration. * Proficiency in speaking and understanding English. Exclusion Criteria: * Must not be color-blind * Current treatment for ADHD/ADD. * History of neurological disorders, including but not limited to the following specified conditions * Epilepsy or seizures (excluding childhood febrile seizures). * Dementia, Parkinson's disease, multiple sclerosis, cerebral aneurysm, or brain tumors. * History of stroke or traumatic brain injury. * Medical conditions or treatments that could interfere with study participation (e.g., unstable cardiac disease, HIV/AIDS, malignancy, or renal impairment). * Prior brain surgery or presence of brain devices/implants (e.g., cochlear implants or aneurysm clips). * Females who are pregnant or breastfeeding. * Use of specific medications, including but not limited to ADHD medications or benzodiazepines, which may interfere with EEG measurements or task performance * Any condition that, in the opinion of the investigator, increases risk or hinders full compliance with the study.
Where this trial is running
Tallahassee, Florida
- Florida State University Psychology Dept Bldg A411 — Tallahassee, Florida, United States (Recruiting)
Study contacts
- Study coordinator: Justin Riddle, PhD
- Email: jr23z@fsu.edu
- Phone: 850-644-9869
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.