Effect of brain stimulation on anxiety symptoms
Intervention Effect of Transcranial Alternating Current Stimulation(tACS) on Anxiety Disorder
This study is testing whether a type of brain stimulation can help people with anxiety feel better and reduce their symptoms.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Anhui Medical University Academic / other |
| Locations | 1 site (Hefei) |
| Trial ID | NCT06026826 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of transcranial alternating current stimulation (tACS) on anxiety symptoms and related somatic issues in patients diagnosed with anxiety disorders. Forty participants will undergo a structured evaluation and receive either active or sham tACS treatment over a week, with assessments conducted before and after the intervention. The study aims to explore the underlying neural mechanisms of anxiety through functional magnetic resonance imaging (fMRI) and various neuropsychological tests. The treatment protocol involves specific electrode placements and stimulation parameters to assess the efficacy of tACS.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 60 with a confirmed diagnosis of anxiety disorder and specific symptom severity.
Not a fit: Patients with severe somatic diseases, other neurological disorders, or those who cannot undergo MRI will not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could provide a novel non-invasive treatment option for patients suffering from anxiety disorders.
How similar studies have performed: Previous studies have shown promising results with tACS in treating various neurological and psychological conditions, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * the patients were diagnosed by more than 2 psychiatrists and met the diagnostic criteria of DSM-5 for anxiety, and HAMA\>14, PHQ-15\>5. the age ranged from 18 to 60 years old, and the length of education was more than 5 years. the visual acuity or corrected visual acuity is normal, right-handed, can cooperate with the completion of various experimental tests. Exclusion Criteria: * accompanied by severe somatic diseases, such as severe heart, liver, renal insufficiency and so on. accompanied by other neurological diseases, such as stroke, epilepsy and so on. pregnant and lactating women. accompanied by other mental disorders, such as drug abuse, schizophrenia, schizophrenic affective disorder, hysteria, autism and so on. patients with MRI taboos or factors affecting imaging quality, such as cardiac pacemaker, cochlear implant, cardio-cerebrovascular metal stent, metal denture, etc. those who could not cooperate with those who completed the relevant experiments, such as patients with depressive stupor, claustrophobia and so on.
Where this trial is running
Hefei
- Anhui Medical University — Hefei, China (Recruiting)
Study contacts
- Study coordinator: Wang Kai, PhD
- Email: wangkai1964@126.com
- Phone: +86-0551-62923704
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.