Effect of birth control pills on migraine symptoms
Impact of Combined Oral Contraceptive Pills on Migraine, a Randomized Controlled Trial
This study is testing how birth control pills affect migraine symptoms in women to see if they can help improve their headaches.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 18 Years to 55 Years |
| Sex | Female |
| Sponsor | Kafrelsheikh University Academic / other |
| Locations | 1 site (Kafr ash Shaykh) |
| Trial ID | NCT06509503 on ClinicalTrials.gov |
What this trial studies
This study evaluates how combined oral contraceptive pills (COCs) influence migraine characteristics and treatment responses in female patients. Researchers will collect data through questionnaires to assess demographic and clinical features of migraineurs, including attack frequency, duration, and pain intensity. The study will also examine vascular risk factors and conduct neurological and physical examinations to establish a comprehensive migraine history. The goal is to better understand the impact of hormonal contraceptives on women suffering from migraines.
Who should consider this trial
Good fit: Ideal candidates are female migraine patients aged 18-55 who are currently using combined oral contraceptives or mechanical contraceptive methods.
Not a fit: Patients with major neurological conditions, pregnant or lactating women, and those with contraindications to specific medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for female migraine patients using hormonal contraceptives.
How similar studies have performed: Previous studies have shown varying results regarding the impact of hormonal contraceptives on migraines, making this approach both relevant and necessary for further exploration.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * female migraine patients on COCs or mechanical contraceptive methods, according to the International Classification of Headache Disorders 3rd edition, aged 18-55 years Exclusion Criteria: 1. Patients with major neurological conditions such as (epilepsy, ischemic or hemorrhagic stroke, multiple sclerosis, mitochondrial diseases, and brain tumors). 2. pregnant, lactating, and menopausal patients. 3. Patients with any contraindications to ibuprofen or propranolol.
Where this trial is running
Kafr ash Shaykh
- Kafr Elsheikh University Hospital — Kafr ash Shaykh, Egypt (Recruiting)
Study contacts
- Study coordinator: mohamed G. Zeinhom, MD
- Email: mohamed_gomaa@med.kfs.edu.eg
- Phone: 2001009606828
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.