Effect of ankle manipulation on proprioception in stroke patients
Official title: The Effect of Talocrural Joint Manipulation on Ankle Proprioception in Post-Stroke Patients
Run by Bitlis Eren University · NCT06849076 · Data updated 2026-11-12
This study is testing if ankle manipulation can help improve balance and body awareness in stroke patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years to 75 Years |
| Sex | All |
| Enrollment | 26 (estimated) |
| Sponsor | Bitlis Eren University Academic / other |
| Locations | 1 site (Bolu, Merkez) |
| Status | Recruiting |
| Started | April 14, 2025 |
| Main results expected | November 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | July 27, 2026 |
| Trial ID | NCT06849076 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are stroke patients aged 45 to 75 who have had their stroke at least two months prior and have a Mini-Mental State Examination score of 24 or higher.
✕Probably not a fit
Patients with severe osteoarthritis, other neurological disorders, or recent lower extremity injuries may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates how talocrural joint manipulation affects ankle proprioception in patients who have experienced a stroke. It employs a randomized crossover design, where participants will receive both placebo and active manipulation treatments. A minimum of 26 stroke patients will be enrolled, and their proprioceptive abilities will be assessed following each intervention. The goal is to determine if the manipulation can enhance proprioceptive function post-stroke.
Why it matters
Potential benefit: If successful, this intervention could improve proprioception in stroke patients, potentially aiding their rehabilitation and recovery.
How similar studies have gone: While the specific approach of talocrural manipulation in stroke patients is novel, similar studies have shown positive outcomes in proprioceptive enhancement through joint manipulation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Two months or longer elapsed since the stroke, 2. A Mini-Mental State Examination score of 24 or higher, 3. Being between 45 and 75 years of age, 4. Having a Brunnstrom stage of 4 or above Exclusion Criteria: 1. The presence of severe osteoarthritis in the lower extremity, 2. The presence of cancer or diabetic neuropathy, 3. The presence of vestibular disorder, 4. The presence of lower extremity ulceration or amputation, 5. Hemodynamic instability, 6. The presence of other neurological disorders (such as multiple sclerosis, Parkinson's disease), 7. Having experienced an acute lower extremity injury in the last six weeks, 8. History of lower extremity surgery 9. Lack of available range of motion values required for the ankle proprioception test
Where it's running
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Bolu İzzet Baysal Fizik Tedavi ve Rehabilitasyon Eğitim ve Araştırma Hastanesi
Bolu, Merkez, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: ömer dursun, Asst. Prof. — Bitlis Eren University
- Study coordinator: ömer dursun, Asst. Prof.
- Email: fztomrdrsn@gmail.com
- Phone: 5426088687
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
-
Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
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AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
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Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
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Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
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Dual-task balance training plus computer-based cognitive training after stroke
In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.