Effect of ankle manipulation on proprioception in stroke patients

The Effect of Talocrural Joint Manipulation on Ankle Proprioception in Post-Stroke Patients

Not applicable Interventional Bitlis Eren University · NCT06849076

This study is testing if ankle manipulation can help improve balance and body awareness in stroke patients.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment26 (estimated)
Ages45 Years to 75 Years
SexAll
SponsorBitlis Eren University Academic / other
Locations1 site (Bolu, Merkez)
Trial IDNCT06849076 on ClinicalTrials.gov

What this trial studies

This study investigates how talocrural joint manipulation affects ankle proprioception in patients who have experienced a stroke. It employs a randomized crossover design, where participants will receive both placebo and active manipulation treatments. A minimum of 26 stroke patients will be enrolled, and their proprioceptive abilities will be assessed following each intervention. The goal is to determine if the manipulation can enhance proprioceptive function post-stroke.

Who should consider this trial

Good fit: Ideal candidates are stroke patients aged 45 to 75 who have had their stroke at least two months prior and have a Mini-Mental State Examination score of 24 or higher.

Not a fit: Patients with severe osteoarthritis, other neurological disorders, or recent lower extremity injuries may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could improve proprioception in stroke patients, potentially aiding their rehabilitation and recovery.

How similar studies have performed: While the specific approach of talocrural manipulation in stroke patients is novel, similar studies have shown positive outcomes in proprioceptive enhancement through joint manipulation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Two months or longer elapsed since the stroke,
2. A Mini-Mental State Examination score of 24 or higher,
3. Being between 45 and 75 years of age,
4. Having a Brunnstrom stage of 4 or above

Exclusion Criteria:

1. The presence of severe osteoarthritis in the lower extremity,
2. The presence of cancer or diabetic neuropathy,
3. The presence of vestibular disorder,
4. The presence of lower extremity ulceration or amputation,
5. Hemodynamic instability,
6. The presence of other neurological disorders (such as multiple sclerosis, Parkinson's disease),
7. Having experienced an acute lower extremity injury in the last six weeks,
8. History of lower extremity surgery
9. Lack of available range of motion values required for the ankle proprioception test

Where this trial is running

Bolu, Merkez

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeProprioception
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.