Clinical trial Recruiting at 1 site Interventional Ages 45 to 75

Effect of ankle manipulation on proprioception in stroke patients

Official title: The Effect of Talocrural Joint Manipulation on Ankle Proprioception in Post-Stroke Patients

Run by Bitlis Eren University · NCT06849076 · Data updated 2026-11-12

This study is testing if ankle manipulation can help improve balance and body awareness in stroke patients.

Quick facts

Study typeInterventional
Ages45 Years to 75 Years
SexAll
Enrollment26 (estimated)
SponsorBitlis Eren University
Academic / other
Locations1 site (Bolu, Merkez)
StatusRecruiting
StartedApril 14, 2025
Main results expectedNovember 1, 2026
Study endsDecember 1, 2026
Registry record updatedJuly 27, 2026
Trial IDNCT06849076 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are stroke patients aged 45 to 75 who have had their stroke at least two months prior and have a Mini-Mental State Examination score of 24 or higher.

Probably not a fit

Patients with severe osteoarthritis, other neurological disorders, or recent lower extremity injuries may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how talocrural joint manipulation affects ankle proprioception in patients who have experienced a stroke. It employs a randomized crossover design, where participants will receive both placebo and active manipulation treatments. A minimum of 26 stroke patients will be enrolled, and their proprioceptive abilities will be assessed following each intervention. The goal is to determine if the manipulation can enhance proprioceptive function post-stroke.

Why it matters

Potential benefit: If successful, this intervention could improve proprioception in stroke patients, potentially aiding their rehabilitation and recovery.

How similar studies have gone: While the specific approach of talocrural manipulation in stroke patients is novel, similar studies have shown positive outcomes in proprioceptive enhancement through joint manipulation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Two months or longer elapsed since the stroke,
2. A Mini-Mental State Examination score of 24 or higher,
3. Being between 45 and 75 years of age,
4. Having a Brunnstrom stage of 4 or above

Exclusion Criteria:

1. The presence of severe osteoarthritis in the lower extremity,
2. The presence of cancer or diabetic neuropathy,
3. The presence of vestibular disorder,
4. The presence of lower extremity ulceration or amputation,
5. Hemodynamic instability,
6. The presence of other neurological disorders (such as multiple sclerosis, Parkinson's disease),
7. Having experienced an acute lower extremity injury in the last six weeks,
8. History of lower extremity surgery
9. Lack of available range of motion values required for the ankle proprioception test

Where it's running

  • Bolu İzzet Baysal Fizik Tedavi ve Rehabilitasyon Eğitim ve Araştırma Hastanesi
    Bolu, Merkez, Turkey (Türkiye)
    Recruiting

Study contacts

  • Principal investigator: ömer dursun, Asst. Prof. — Bitlis Eren University
  • Study coordinator: ömer dursun, Asst. Prof.
  • Email: fztomrdrsn@gmail.com
  • Phone: 5426088687

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.