EFESO: Juvenile-onset eosinophilic fasciitis characterization

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational, multicenter effort to gather clinical, diagnostic, and treatment data on patients diagnosed with juvenile-onset eosinophilic fasciitis from 2000 through 2026. Participants must have been diagnosed before age 18 and have at least six months of follow-up, with data contributed under local informed consent rules. The registry will compare pediatric presentations to adult diagnostic criteria, document the role of skin biopsy in children, and record outcomes with common therapies such as glucocorticoids and methotrexate. Data will come from participating centers in Europe and the United States to better define pediatric diagnostic and therapeutic pathways.

Why it matters

Who can join: the full rules

Inclusion criterai:

All patients diagnosed from 2000 to 31/12/2026

* minimum follow-up 6 months
* Age \<18 years at diagnosis;
* All patients whose informed consent is collected in accordance with current local legislation will also be considered enrollable.

Exclusion Criteria:

* Age ≥18 years at diagnosis;
* Unwilling to participate into the study;
* A follow-up period \< 6 months.

Where it's running

• University of Alabama at Birmingham
  Birmingham, Alabama, United States Recruiting
• SUNY Upstate Pediatric Rheumatology
  Syracuse, New York, United States Recruiting
• Children's Hospital Zagreb
  Zagreb, Croatia Recruiting
• Meyer Children's Hospital IRCCS
  Florence, Fi, Italy Recruiting
• IRCCS Giannina Gaslini,
  Genova, Italy Recruiting
• Iuliu Hatieganu University of Medicine and Pharmacy
  Cluj-Napoca, Romania Recruiting

Study contacts

• Study coordinator: Edoardo Marrani
• Email: edoardo.marrani@meyer.it
• Phone: +390555662913

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.