Education and support program for African American patients with advanced kidney disease

Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy

NA · University of Chicago · NCT06397456

This study is testing a 12-week education and support program for African American patients with advanced kidney disease to see if it helps them better manage their condition and plan for treatment.

Quick facts

PhaseNA
Study typeInterventional
Enrollment180 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorUniversity of Chicago (other)
Locations1 site (Chicago, Illinois)
Trial IDNCT06397456 on ClinicalTrials.gov

What this trial studies

The Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP-RRT) is a 12-week intervention designed for hospitalized African Americans with advanced chronic kidney disease (CKD). This program provides hospital- and community-based education, navigation, and self-management support to improve patient knowledge and self-efficacy regarding CKD and renal replacement therapy (RRT) planning. Participants will be randomized to receive either the iPREP-RRT intervention or enhanced usual care, with the aim of enhancing CKD self-management and RRT planning through various communication methods. The study evaluates the effectiveness of both hospital-based and community-based interventions in improving patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are hospitalized African American patients aged 18 to 70 with advanced CKD (Stage 3B or above).

Not a fit: Patients who are non-English speaking, unable to communicate due to their medical status, or currently admitted to the ICU may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly enhance the self-management and treatment planning for African American patients with advanced CKD.

How similar studies have performed: Other studies have shown success with similar educational and support interventions for chronic disease management, indicating potential for positive outcomes in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients over the age of 18 and under 70
* Admitted to the University of Chicago inpatient general medicine service
* Likely hospital stay greater than 48 hours
* Diagnosis of advanced CKD (Stage 3B or above, as determine by problem list, ICD- 10 codes or eGFR\<45 during admission and from previous medical encounters)
* Self-identify as Black or African American

Exclusion Criteria:

* Non-English speaking
* Unable to communicate due to current medical status
* Unable to consent due to mental status
* Expected hospital stay less than 24 hour
* Current admission in ICU

Where this trial is running

Chicago, Illinois

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Chronic Kidney Disease, Hypertension, Hospitalized Patients, African American, Motivational Interviewing

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.