Economic impact of IVIG treatment for PANS

The Unhide™ Project: Economic Impact Study of IVIG Treatment for PANS

Observational Brain Inflammation Collaborative · NCT06818656

This study looks at how IVIG treatment for children with PANS affects families' finances and the children's quality of life.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages2 Years to 89 Years
SexAll
SponsorBrain Inflammation Collaborative Academic / other
Locations1 site (Delafield, Wisconsin)
Trial IDNCT06818656 on ClinicalTrials.gov

What this trial studies

This study is part of the Unhide™ Project, which aims to understand the economic and health impacts of IVIG treatment for Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and PANDAS. It gathers data from families to assess how these conditions affect their financial well-being and the overall quality of life of affected children. Participants will provide insights through surveys, contributing to a broader understanding of the implications of treatment and the condition itself.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with PANDAS or PANS who have either received or sought IVIG treatment.

Not a fit: Patients who have not been diagnosed with PANDAS or PANS or those who do not meet the inclusion criteria will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the economic burden of PANS and PANDAS, potentially leading to improved treatment strategies and support for affected families.

How similar studies have performed: While this study focuses on economic impacts, similar studies on the health outcomes of IVIG treatment for PANS and PANDAS have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals who who have, or have had, a healthcare provider-diagnosed or suspected diagnosis of PANDAS and/or PANS
* Have received IVIG OR have sought and/or been prescribed IVIG but have not received it
* Fluent in English, sufficient to communicate status via the ePRO instrument as required by the protocol
* Is a U.S. resident
* Access to a computer and/or smartphone and the internet, and possessing the ability to operate those devices without assistance from another person (except that children can be assisted by their parents/guardians).

Exclusion Criteria:

* Ward of state
* Failure to meet inclusion criteria

Where this trial is running

Delafield, Wisconsin

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PANDASPANSPANS Pediatric Acute-Onset Neuropsychiatric SyndromePediatric Acute-onset Neuropsychiatric SyndromePediatric Acute-Onset Neuropsychiatric SyndromePediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal InfectionsNatural History StudyIVIG
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.