Eccentric resistance training for people with chronic heart failure
Effects of Eccentric Resistance Training on Ventricle Functions and Aerobic Capacity Among Individuals With Chronic Heart Failure
This study is testing if a special type of strength training can help people with chronic heart failure improve their heart function and ability to exercise better than other training methods.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 84 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Riphah International University Academic / other |
| Locations | 2 sites (Rawalpindi, Punjab Province and 1 other locations) |
| Trial ID | NCT06032780 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effects of eccentric resistance training on heart function and aerobic capacity in individuals diagnosed with chronic heart failure. Participants will be divided into three groups: one receiving eccentric resistance training combined with aerobic training, another receiving traditional resistance training with aerobic training, and a third group focusing solely on aerobic training. The study will assess improvements in ventricle functions and overall exercise capacity through standardized tests. The goal is to identify the most effective training regimen for enhancing physical health in heart failure patients.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with chronic heart failure who are currently on optimal medical therapy and can safely perform lower limb exercises.
Not a fit: Patients with advanced heart failure symptoms (NYHA class IV), those with significant co-existing diseases, or individuals unable to perform the required exercises will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved exercise regimens that enhance heart function and quality of life for patients with chronic heart failure.
How similar studies have performed: While there is limited information on the specific approach of eccentric resistance training in this context, similar studies have shown positive outcomes with various exercise interventions in heart failure populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of Chronic HF and currently stable with optimal medical therapy * Chronic Heart failure with ejection fraction \> 30 % * Patient able to safely perform lower limb exercise will be check by six- minute walk test (6 MWT) Exclusion Criteria: * Those Heart failure patient whose are in acute phase or planed for any immediate medical intervention * Already participating in cardiac rehabilitation * New York Heart Association (NYHA) Classification of HF class IV HF symptoms * Co-existent other disease such as asthma/ COPD/interstitial lung disease. * Symptomatic Second degree or third degree heart block. * ECG with uncontrolled ventricular arrhythmia * Limited Exercise ability due to neurologic or orthopedic impairments of the legs (will cross-check with 6 MWT)
Where this trial is running
Rawalpindi, Punjab Province and 1 other locations
- Pakistan Railway Hospital — Rawalpindi, Punjab Province, Pakistan (Suspended)
- Rawalpindi Institute of Cardiology — Rawalpindi, Punjab Province, Pakistan (Recruiting)
Study contacts
- Principal investigator: Muhammad Iqbal Tariq, PhD* — Riphah International University
- Study coordinator: Muhammad Iqbal Tariq, PhD*
- Email: iqbal.tariq@riphah.edu.pk
- Phone: +923338236752
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.