Eccentric exercise for improving spasticity, walking, and balance in children with cerebral palsy

Effect of Eccentric Exercise Training on Spasticity, Walking and Balance in Individuals With Spastic Cerebral Palsy

NA · Lokman Hekim Üniversitesi · NCT06676540

This study is testing if adding eccentric exercises to regular therapy can help children with cerebral palsy improve their muscle tightness, walking, and balance.

Quick facts

PhaseNA
Study typeInterventional
Enrollment42 (estimated)
Ages6 Years to 18 Years
SexAll
SponsorLokman Hekim Üniversitesi (other gov)
Locations1 site (Ankara)
Trial IDNCT06676540 on ClinicalTrials.gov

What this trial studies

This clinical research investigates the effects of eccentric exercise training on spasticity, walking, and balance in children aged 6-18 with spastic cerebral palsy. The study employs a randomized controlled design with two groups: one receiving neurodevelopmental treatment alone and the other receiving neurodevelopmental treatment combined with eccentric exercise. Participants will undergo physiotherapy sessions twice a week for eight weeks, followed by evaluations to assess changes in spasticity, gait, and balance. The study aims to determine the effectiveness of eccentric exercises on these parameters.

Who should consider this trial

Good fit: Ideal candidates are children aged 6-18 diagnosed with spastic hemiparetic or diparetic cerebral palsy at GMFCS levels I, II, or III.

Not a fit: Patients who have had botox treatment or surgery in the last six months may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve mobility and quality of life for children with spastic cerebral palsy.

How similar studies have performed: While similar studies have explored exercise interventions in cerebral palsy, the specific focus on eccentric exercise is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being between the ages of 6-18 and diagnosed with spastic hemiparetic or spastic diparetic CP,
* Being at level I, II or III according to GMFCS,
* Having increased muscle tone in hip flexor, hip adductor, knee flexor, knee extensor or ankle plantar flexor muscles according to MTS,
* Giving informed consent including detailed information prepared for the study (by parent/guardian).

Exclusion Criteria:

* Having received botox or surgery in the last 6 months.
* Not signing the consent form.
* Having limited cooperation regarding perception or performance of exercises required for the study.
* Having a systemic disease in addition to CP.

Where this trial is running

Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cerebral Palsy, Spastic, Gait Analysis, Postural Balance, Cerebral Palsy, eccentric exercise

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.