Eccentric cycling exercise for patients with chronic kidney disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of an eccentric cycling exercise program on patients with chronic kidney disease (CKD). It aims to assess improvements in body composition, functional capacity, flexibility, muscle strength, exercise capacity, pulmonary function, quality of life, and renal function. Participants will be randomly assigned to one of three groups: eccentric cycling exercise, concentric cycling exercise, or usual care. The study is conducted in collaboration with the Departments of Nephrology and Geriatric Medicine at National Cheng Kung University Hospital in Taiwan.

Why it matters

Who can join: the full rules

This study will be conducted in collaboration with the Departments of Nephrology and Geriatric Medicine at National Cheng Kung University Hospital, Taiwan. Participants will be recruited as voluntary subjects from outpatient clinics. The attending physician will assess eligible patients. After the study's purpose and methodology are explained by the research staff and patients consent to participate, block randomization will be used to assign participants into one of three groups randomly. The allocation results will be securely stored by the principal investigator.

Inclusion Criteria:

* (1) Clinical diagnosis of CKD
* (2) eGFR \<60 ml/min/1.73m\^2 or undergoing routine dialysis
* (3) Must be able to communicate normally, understand and comply with instructions.
* (4) Must be able to walk independently.

Exclusion Criteria:

* (1) Clinical diagnosis of acute renal failure
* (2) Hospitalization for acute illness within the past three months
* (3) Clinical diagnosis of severe joint disease and lower extremity surgery
* (4) Clinical diagnosis of severe neurological disease
* (5) Clinical diagnosis of severe cardiovascular disease
* (6) Unconsciousness or lack of ability to cooperate with the assessment

Where it's running

• National Cheng Kung University Hostipal
  Tainan, Taiwan, Taiwan Recruiting

Study contacts

• Study coordinator: Kun-Ling Tsai, Ph.D.
• Email: kunlingtsai@mail.ncku.edu.tw
• Phone: 886-6-2353535 Ext. 6219

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.