Eatwell nutrition program to improve diets linked to cancer prevention

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, two-arm trial will enroll 236 index adults plus 236 adult household members (N=472) who score low on WCRF/AICR dietary guidelines and randomize them to the Eatwell intervention or traditional nutrition education. The Eatwell program focuses on healthier grocery choices, eating at home more often, and strategies for handling temptations when eating out, delivered via sessions and monthly emails with household support. The primary outcome is a total dietary adherence score calculated using NCI's standardized scoring system, with secondary outcomes including grams/day of fruits, vegetables, and fiber; percent of calories from ultra-processed foods; grams/week of red and processed meat; grams/day of sugar-sweetened beverages; and biomarkers of inflammation measured from blood draws. Participants will need technology for videoconferencing and must be willing to provide blood samples at a partnered commercial laboratory.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 or older
* Access to technology necessary to receive emails and join videoconferencing meetings
* Ability to read and speak English
* Willingness to be randomized to either study condition, including ability and willingness to attend intervention sessions
* Ability and willingness to attend intervention sessions, receive monthly email messages, and serve in support role if index participant in household is assigned to Eatwell condition
* Able and willing to visit a commercial laboratory partnered with this project (e.g., Labcorp) in order to have their blood drawn at the time of study visits
* Low adherence to WCRF/AICR's four dietary guidelines (operationalized as a level of intake, based on brief self-report questions administered during phone screening, that corresponds to a score of 2 or less in the Shams-White method of dietary adherence scoring)
* Share a household (i.e., a private residence with a shared living space, including kitchen) with an adult who provides informed consent, meets eligibility criteria, and anticipates remaining in this household for the majority of the next 18 months
* Agree that they will not join another intervention study run by this study team in the next 18 months
* Successful completion by self and household member of all enrollment and baseline data collection tasks
* Have an email that they regularly check and willingness to use that for corresponding to study staff
* Weight at baseline of 396 lbs or less, as the digital scales used for measurement are not able to obtain measurements for weights higher than this

Exclusion Criteria:

* A medical or psychiatric condition, including self-reported history of anorexia nervosa or bulimia nervosa, that may limit appropriateness of or ability to comply with dietary recommendations
* A psychiatric condition, including self-reported history of anorexia nervosa or bulimia nervosa, that may make it difficult or inappropriate for household member to serve in support role
* Currently taking medication that can substantively change appetite or eating behavior, including using of a GLP-1 medication
* Planning to enroll in another lifestyle modification program in the next 18 months
* History of bariatric surgery
* Currently pregnant or planning to become pregnant in the next 18 months
* Type 1 Diabetes

Where it's running

• Drexel University
  Philadelphia, Pennsylvania, United States Recruiting

Study contacts

• Study coordinator: Research Coordinator, BA
• Email: aeu26@drexel.edu
• Phone: 724-619-1461

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.