Early temperature management for heat stroke patients
Official title: Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients
Run by Second Affiliated Hospital, Zhejiang University, School of Medicine · NCT06537557 · Data updated 2026-11-12
This study is testing a new way to quickly lower body temperature in heat stroke patients when they arrive at the emergency room to see if it helps them recover better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 188 (estimated) |
| Sponsor | Second Affiliated Hospital, Zhejiang University, School of Medicine Academic / other |
| Locations | 7 sites (Guli, Zhejiang and 6 other locations) |
| Status | Recruiting |
| Started | July 1, 2024 |
| Main results expected | September 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | May 27, 2026 |
| Trial ID | NCT06537557 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients admitted to the emergency department with a diagnosis of heat stroke.
✕Probably not a fit
Patients who are transferred from another hospital with a body temperature below 39.5°C or those with severe comorbidities may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on implementing a systematic temperature management protocol for patients diagnosed with heat stroke upon their admission to the emergency department. Heat stroke is a critical condition characterized by dangerously high body temperatures and can lead to severe organ dysfunction and death if not treated promptly. The protocol aims to standardize the approach to rapidly reduce core body temperature, thereby minimizing cellular damage and improving patient outcomes. The study will evaluate the effectiveness of this protocol in a clinical setting across multiple hospitals in Zhejiang, China.
Why it matters
Potential benefit: If successful, this protocol could significantly improve survival rates and recovery outcomes for patients suffering from heat stroke.
How similar studies have gone: While there is limited data on systematic protocols for heat stroke management, similar approaches in emergency temperature management have shown promise in other critical conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients admitted to the emergency department and diagnosed with heat stroke according to the China expert consensus on Heat Stroke Exclusion Criteria: * transferred from another hospital and body temperature \< 39.5℃; discharged within 4 hours, and subsequent body temperature or outcomes were unavailable; required immediate cardiopulmonary resuscitation; had other serious diseases, such as massive cerebral haemorrhage or severe trauma.
Where it's running
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Yongkang No.1 People's Hospital
Guli, Zhejiang, China Recruiting -
Dongyang People's Hospital
Dongyang, China Recruiting -
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hanzhou, China Recruiting -
Jinhua Municipal Central Hospital
Jinhua, China Recruiting -
Jinhua People's Hospital
Jinhua, China Recruiting -
Lanxi People's Hospital
Lanxi, China Recruiting
Show 1 more location
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Yiwu Central Hospital
Yiwu, China Recruiting
Study contacts
- Study coordinator: Xiuqin Feng
- Email: fengxiuqin@zju.edu.cn
- Phone: 13757119151
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.