Clinical trial Recruiting at 7 sites Interventional Ages 18 and up

Early temperature management for heat stroke patients

Official title: Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients

Run by Second Affiliated Hospital, Zhejiang University, School of Medicine · NCT06537557 · Data updated 2026-11-12

This study is testing a new way to quickly lower body temperature in heat stroke patients when they arrive at the emergency room to see if it helps them recover better.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment188 (estimated)
SponsorSecond Affiliated Hospital, Zhejiang University, School of Medicine
Academic / other
Locations7 sites (Guli, Zhejiang and 6 other locations)
StatusRecruiting
StartedJuly 1, 2024
Main results expectedSeptember 30, 2026
Study endsDecember 30, 2026
Registry record updatedMay 27, 2026
Trial IDNCT06537557 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients admitted to the emergency department with a diagnosis of heat stroke.

Probably not a fit

Patients who are transferred from another hospital with a body temperature below 39.5°C or those with severe comorbidities may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on implementing a systematic temperature management protocol for patients diagnosed with heat stroke upon their admission to the emergency department. Heat stroke is a critical condition characterized by dangerously high body temperatures and can lead to severe organ dysfunction and death if not treated promptly. The protocol aims to standardize the approach to rapidly reduce core body temperature, thereby minimizing cellular damage and improving patient outcomes. The study will evaluate the effectiveness of this protocol in a clinical setting across multiple hospitals in Zhejiang, China.

Why it matters

Potential benefit: If successful, this protocol could significantly improve survival rates and recovery outcomes for patients suffering from heat stroke.

How similar studies have gone: While there is limited data on systematic protocols for heat stroke management, similar approaches in emergency temperature management have shown promise in other critical conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients admitted to the emergency department and diagnosed with heat stroke according to the China expert consensus on Heat Stroke

Exclusion Criteria:

* transferred from another hospital and body temperature \< 39.5℃; discharged within 4 hours, and subsequent body temperature or outcomes were unavailable; required immediate cardiopulmonary resuscitation; had other serious diseases, such as massive cerebral haemorrhage or severe trauma.

Where it's running

  • Yongkang No.1 People's Hospital
    Guli, Zhejiang, China
    Recruiting
  • Dongyang People's Hospital
    Dongyang, China
    Recruiting
  • The Second Affiliated Hospital of Zhejiang University School of Medicine
    Hanzhou, China
    Recruiting
  • Jinhua Municipal Central Hospital
    Jinhua, China
    Recruiting
  • Jinhua People's Hospital
    Jinhua, China
    Recruiting
  • Lanxi People's Hospital
    Lanxi, China
    Recruiting
Show 1 more location
  • Yiwu Central Hospital
    Yiwu, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.