Early temperature management for heat stroke patients

Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients

Not applicable Interventional Second Affiliated Hospital, School of Medicine, Zhejiang University · NCT06537557

This study is testing a new way to quickly lower body temperature in heat stroke patients when they arrive at the emergency room to see if it helps them recover better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment188 (estimated)
Ages18 Years and up
SexAll
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University Academic / other
Locations7 sites (Guli, Zhejiang and 6 other locations)
Trial IDNCT06537557 on ClinicalTrials.gov

What this trial studies

This study focuses on implementing a systematic temperature management protocol for patients diagnosed with heat stroke upon their admission to the emergency department. Heat stroke is a critical condition characterized by dangerously high body temperatures and can lead to severe organ dysfunction and death if not treated promptly. The protocol aims to standardize the approach to rapidly reduce core body temperature, thereby minimizing cellular damage and improving patient outcomes. The study will evaluate the effectiveness of this protocol in a clinical setting across multiple hospitals in Zhejiang, China.

Who should consider this trial

Good fit: Ideal candidates for this study are patients admitted to the emergency department with a diagnosis of heat stroke.

Not a fit: Patients who are transferred from another hospital with a body temperature below 39.5°C or those with severe comorbidities may not benefit from this study.

Why it matters

Potential benefit: If successful, this protocol could significantly improve survival rates and recovery outcomes for patients suffering from heat stroke.

How similar studies have performed: While there is limited data on systematic protocols for heat stroke management, similar approaches in emergency temperature management have shown promise in other critical conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients admitted to the emergency department and diagnosed with heat stroke according to the China expert consensus on Heat Stroke

Exclusion Criteria:

* transferred from another hospital and body temperature \< 39.5℃; discharged within 4 hours, and subsequent body temperature or outcomes were unavailable; required immediate cardiopulmonary resuscitation; had other serious diseases, such as massive cerebral haemorrhage or severe trauma.

Where this trial is running

Guli, Zhejiang and 6 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Heat Stroke
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.