Early return of atrial fibrillation after pulsed field ablation and long‑term risk

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, real-world study follows adults undergoing first-time pulsed field ablation for atrial fibrillation at West China Hospital and records arrhythmia using 24-hour Holter monitors at 1, 3, 6, and 12 months post-procedure. Investigators will analyze early recurrence within different time windows and compare those patterns to late recurrence using large-scale data methods. The goal is to develop a risk stratification tool and define an evidence-based blanking period after pulsed field ablation. The work uses single-center clinical data from Chengdu, China to identify prognostic indicators for short- and long-term outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged ≥18 years
* Study participants diagnosed with atrial fibrillation (AF) and scheduled to undergo pulsed field ablation
* Study participants undergoing their first ablation procedure for AF

Exclusion Criteria:

* Study participants with any known contraindications to the pulsed field ablation system, anticoagulation therapy, use of contrast agents, or atrial fibrillation ablation
* Those who have previously undergone atrial fibrillation ablation, or have severe mitral stenosis, valve replacement, or various cardiac surgeries.

Where it's running

• West China Hospital, Sichuan University
  Chengdu, Sichuan, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.