Early removal of chest tubes after surgery for spontaneous pneumothorax
Official title: Early Chest Tube Removal After Surgery for Primary Spontaneous Pneumothorax: A Randomized Controlled Trial
Run by Swedish Medical Center · NCT06411431 · Data updated 2026-11-12
This study tests if taking out chest tubes a day earlier after surgery for a collapsed lung helps patients feel better and leave the hospital sooner without increasing the chance of problems.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Swedish Medical Center Academic / other |
| Drugs / interventions | chemotherapy, radiation, prednisone |
| Locations | 1 site (Seattle, Washington) |
| Status | Recruiting |
| Started | October 3, 2023 |
| Main results expected | December 2025 |
| Study ends | December 2027 |
| Registry record updated | May 16, 2025 |
| Trial ID | NCT06411431 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 undergoing VATS with blebectomy/wedge resection and chemical pleurodesis for primary spontaneous pneumothorax.
✕Probably not a fit
Patients with secondary spontaneous pneumothorax, prior chest surgery, or those who are immunocompromised will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effects of early chest tube removal on patients undergoing video-assisted thoracoscopic surgery (VATS) for primary spontaneous pneumothorax (PSP). Participants will be randomly assigned to either early removal on postoperative day 1 or standard removal on postoperative day 2. The study aims to determine if early removal leads to similar recurrence rates while reducing hospital stay and discomfort. The trial will include adult patients who meet specific eligibility criteria and will be conducted at multiple centers.
Why it matters
Potential benefit: If successful, this approach could lead to shorter hospital stays and reduced discomfort for patients recovering from surgery for spontaneous pneumothorax.
How similar studies have gone: While this approach is novel in the context of chest tube management for PSP, similar studies in other surgical contexts have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient undergoing video assisted thoracoscopic surgery with blebectomy/wedge resection and chemical pleurodesis for primary spontaneous pneumothorax * Adult patients (\> 18 years) Exclusion Criteria: * Subjects with history of chest radiation or prior ipsilateral chest surgery * Tuberculosis or other infectious etiology * Secondary spontaneous pneumothorax (COPD, cancer, cystic fibrosis, connective tissue disease, sarcoidosis, catamenial, etc.) * Pneumothorax due to trauma * Hemothorax or hydropneumothorax * Immunocompromised subjects: neutropenic, leukopenia, or subjects taking immunosuppressive medication such as chemotherapy, transplant medications, steroid (≥5 mg of prednisone or equivalent), etc. * Interstitial lung disease * Children (\<18) * Pregnant women * Adults unable to consent for themselves * Prisoners
Where it's running
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Swedish Cancer Institute
Seattle, Washington, United States Recruiting
Study contacts
- Study coordinator: Brian Louie, M.D.
- Email: brian.louie@swedish.org
- Phone: 206-215-6800
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Improving chest tube and pain management after surgery for spontaneous pneumothorax
This study is testing whether taking out chest tubes right after surgery for a collapsed lung can help patients recover faster and feel less pain compared to keeping them in for several days.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.