Early partial weight-bearing to improve recovery after pelvic fixation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized trial comparing immediate partial weight-bearing with delayed weight-bearing in adults who had surgical fixation for traumatic pelvic fractures. Participants will be adults 18 to 55 with Type B fractures or Type C fractures with stable fixation and an excellent-to-good radiologic reduction. Primary outcomes include function, pain, gait, muscle strength, radiographic quality of reduction, and quality of life, with monitoring for complications. The trial is conducted at the Trauma Hospital, Assiut University, and excludes patients with bilateral unstable pelvic disruptions after fixation, concomitant lower-limb fractures that prevent weight-bearing, spinal cord injury, or active bone infection.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 to 55 years
* Traumatic fractures indicated for pelvic fixation.
* All Types B after stable anterior and / or posterior fixation.
* Type C, Stable fixation:

Posterior fixation by triangular osteosynthesis. oTrans-iliac trans-sacral screw fixation or Trans iliac plate or posterior infex combined with anterior fixation.

• Excellent to good quality of fracture reduction by Matta and Tornetta radiological assessment.

Exclusion Criteria:

* Associated lower extremity fractures that independently restrict or contraindicate weight-bearing activities.
* Bilateral unstable after fixation pelvic ring disruption.
* Patients with associated spinal cord injury, as neurological deficits may alter gait, functional recovery, and weight-bearing capacity, thereby affecting the validity and generalizability of the outcome measures.
* Current history of acute systemic infection, active Bone inflammatory disease, (e.g., osteomyelitis, chronic non-bacterial osteitis), or malignancy, which may compromise the healing process, confound clinical outcomes, or pose additional medical risks during rehabilitation.
* Uncontrolled Diabetes
* Cancer
* Active infection
* Morbid obesity (BMI \> 40)
* Alcohol use disorder (AUD). Alcohol abuse as defined by the National Institute on Alcohol Abuse and Alcoholism: "Drinking at Low Risk for Developing Alcohol Use Disorder: For women, low-risk drinking is defined as no more than 3 drinks on any single day and no more than 7 drinks per week. For men, it is defined as no more than 4 drinks on any single day and no more than 14 drinks per week. NIAAA research shows that only about 2 in 100 people who drink within these limits have AUD".
* Claustrophobia
* Pregnant woman
* Inability to follow study protocol (e.g., lack of ability to attend visits or comprehend instructions)
* Any psychiatric illness that would prevent comprehension of the details and nature of the study and interfere with follow-up clinical visits
* Any clinical finding that would place the patient at health risk, impact the study, or affect the completion of the study

Where it's running

• Trauma Hospital, Assiut University
  Asyut, Asyut Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Hager Emad Abdelzaher, Masters Candidate
• Email: Hager.Emad@med.aun.edu.eg
• Phone: 00201555726135

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pelvic Ring Fragility Fractures: Are Surgery or No Surgery Better for Older Adults?

  This study tests whether surgical stabilization or nonoperative care is best for fragility pelvic fractures in adults 60 and older, by seeing if patients and surgeons would participate in a randomized trial and by checking data collection feasibility.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07351123

• Geriatric pelvic ring fracture: see if surgery helps walking patterns

  This study tests whether surgical fixation improves walking metrics in older adults with pelvic ring fractures compared to non-surgical care.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT07608107

• Comparing fixation methods for specific pelvic ring injuries

  This study is testing whether fixing pelvic ring injuries from the front or back first leads to better recovery and fewer problems for people with certain types of pelvic injuries.

  Recruiting Ain Shams University · Cairo · NCT06792305

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.