Early loading of dental implants in the front of the mouth with bone defects
A Prospective Clinical Study to Evaluate the Outcome of Early Loading of Implants in the Maxillary Anterior Region With Alveolar Bone Defects
This study is testing whether putting dental implants in the front of the mouth sooner rather than later helps people with bone defects have better results and satisfaction.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | The Dental Hospital of Zhejiang University School of Medicine Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT06068231 on ClinicalTrials.gov |
What this trial studies
This study compares the outcomes of early loading versus conventional loading of dental implants in patients with alveolar bone defects in the maxillary anterior region. It aims to assess factors such as marginal bone resorption, implant success rates, complication rates, soft tissue conditions, and patient satisfaction. The research employs a prospective clinical control design and three-dimensional finite element analysis to gather comprehensive data. Patients will be recruited from the Oral Implant Center of Stomatology Hospital Affiliated to Zhejiang University School of Medicine from July 2022 to June 2025.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-60 with a single missing upper anterior tooth and a specific type of bone defect who can undergo guided bone regeneration.
Not a fit: Patients with multiple missing teeth or those with systemic diseases or other types of bone defects may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the waiting time for patients needing dental implants, enhancing both function and aesthetics sooner.
How similar studies have performed: Previous studies have shown promising results with early loading techniques in similar contexts, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age: 18-60 years; 2. Gender: Male or Female; 3. Patients with a single missing upper anterior tooth and a labial open-type single-wall bone defect who underwent simultaneous guided bone regeneration (GBR) surgery; 4. Patients choosing the ITI implant system; 5. Patients without a history of systemic diseases such as cardiovascular disease, hypertension, diabetes, etc.; 6. Patients with no history of periodontal disease or have undergone periodontal treatment and can maintain good oral hygiene with no smoking history; 7. Patients without a history of radiation therapy, hepatitis, tuberculosis, or any familial hereditary diseases; 8. Patients with a normal anterior occlusion. Exclusion Criteria: 1. Patients with bone defects other than labial open-type single-wall bone defects in the anterior region; 2. Patients with multiple consecutive missing upper anterior teeth; 3. Patients with a history of systemic diseases, infectious diseases, or familial hereditary diseases; 4. Patients with poor oral hygiene; 5. Patients with bruxism or teeth clenching.
Where this trial is running
Hangzhou, Zhejiang
- Stomatology Hospital Affiliated to Zhejiang University School of Medicine — Hangzhou, Zhejiang, China (Recruiting)
Study contacts
- Principal investigator: Yixun Chen — Stomatology Hospital Affiliated to Zhejiang University School of Medicine
- Study coordinator: Entang Wang
- Email: wet_email@163.com
- Phone: 13616719380
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.