Clinical trial Recruiting at 1 site Early Phase 1 Interventional Ages 5 to 17

Early IV Magnesium for Moderate Asthma Attacks in Children

Official title: Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation

Run by University of Oklahoma · NCT06137040 · Data updated 2026-11-12

This study tests if giving magnesium right away helps children aged 5-17 with moderate asthma attacks feel better and leave the emergency room faster.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Ages5 Years to 17 Years
SexAll
Enrollment100 (estimated)
SponsorUniversity of Oklahoma
Academic / other
Locations1 site (Oklahoma City, Oklahoma)
StatusRecruiting
StartedNovember 30, 2023
Main results expectedMay 31, 2025
Study endsMay 31, 2025
Registry record updatedDecember 6, 2024
Trial IDNCT06137040 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are children aged 5-17 who present with a moderate asthma exacerbation.

Probably not a fit

Patients with chronic medical conditions or those who are pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of administering magnesium sulfate within the first hour of treatment for children aged 5-17 experiencing moderate asthma exacerbations. Patients presenting to the OU Children's Hospital Emergency Department will be assessed and those with a respiratory score indicating moderate exacerbation will be approached for consent. Eligible participants will be randomized to receive either early magnesium sulfate treatment or standard care as determined by their provider. The study aims to evaluate outcomes such as length of stay in the emergency department and hospital, as well as the need for respiratory support.

Why it matters

Potential benefit: If successful, this approach could reduce hospital admissions and improve recovery times for children experiencing moderate asthma attacks.

How similar studies have gone: Other studies have shown promising results with magnesium sulfate in asthma management, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ages 5-17 years old
* Presents to the ED with a respiratory score in the "Moderate" range (6
* Parent(s)/Caregiver(s) speak English

Exclusion Criteria:

* Patients with chronic medical conditions including chronic pulmonary disease (other than asthma), cerebral palsy, congenital heart disease, tracheostomy dependent, myasthenia gravis patients
* Patients who are pregnant
* Parent(s)/Caregiver(s) do not speak English

Where it's running

  • Oklahoma Children's Hospital
    Oklahoma City, Oklahoma, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.