Early IV Magnesium for Moderate Asthma Attacks in Children
Official title: Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation
Run by University of Oklahoma · NCT06137040 · Data updated 2026-11-12
This study tests if giving magnesium right away helps children aged 5-17 with moderate asthma attacks feel better and leave the emergency room faster.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 5 Years to 17 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | University of Oklahoma Academic / other |
| Locations | 1 site (Oklahoma City, Oklahoma) |
| Status | Recruiting |
| Started | November 30, 2023 |
| Main results expected | May 31, 2025 |
| Study ends | May 31, 2025 |
| Registry record updated | December 6, 2024 |
| Trial ID | NCT06137040 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children aged 5-17 who present with a moderate asthma exacerbation.
✕Probably not a fit
Patients with chronic medical conditions or those who are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of administering magnesium sulfate within the first hour of treatment for children aged 5-17 experiencing moderate asthma exacerbations. Patients presenting to the OU Children's Hospital Emergency Department will be assessed and those with a respiratory score indicating moderate exacerbation will be approached for consent. Eligible participants will be randomized to receive either early magnesium sulfate treatment or standard care as determined by their provider. The study aims to evaluate outcomes such as length of stay in the emergency department and hospital, as well as the need for respiratory support.
Why it matters
Potential benefit: If successful, this approach could reduce hospital admissions and improve recovery times for children experiencing moderate asthma attacks.
How similar studies have gone: Other studies have shown promising results with magnesium sulfate in asthma management, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ages 5-17 years old * Presents to the ED with a respiratory score in the "Moderate" range (6 * Parent(s)/Caregiver(s) speak English Exclusion Criteria: * Patients with chronic medical conditions including chronic pulmonary disease (other than asthma), cerebral palsy, congenital heart disease, tracheostomy dependent, myasthenia gravis patients * Patients who are pregnant * Parent(s)/Caregiver(s) do not speak English
Where it's running
-
Oklahoma Children's Hospital
Oklahoma City, Oklahoma, United States Recruiting
Study contacts
- Principal investigator: Ryan McKee, MD — University of Oklahoma
- Study coordinator: Ryan McKee, MD
- Email: ryan-mckee@ouhsc.edu
- Phone: 4056308997
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.