Early discharge with virtual follow-up for low-risk STEMI patients

Virtual Ward-Assisted Very earLy dIschArge of Low-rIsk STEMI patieNTs: the VALIANT-STEMI Trial

NA · The Leeds Teaching Hospitals NHS Trust · NCT06731257

This study is testing if low-risk heart attack patients can safely go home within 24 hours and have follow-up care by phone instead of staying in the hospital longer.

Quick facts

PhaseNA
Study typeInterventional
Enrollment600 (estimated)
Ages18 Years to 99 Years
SexAll
SponsorThe Leeds Teaching Hospitals NHS Trust (other)
Locations1 site (Leeds)
Trial IDNCT06731257 on ClinicalTrials.gov

What this trial studies

This trial investigates the safety and feasibility of early discharge (within 24 hours) for low-risk patients who have undergone successful treatment for ST elevation myocardial infarction (STEMI). Participants will be randomized to receive either standard care or early discharge with virtual follow-up via telephone. The primary outcome will be hospital readmission or all-cause mortality within 30 days post-discharge. The goal is to determine if this approach can reduce hospital stay while maintaining patient safety and well-being.

Who should consider this trial

Good fit: Ideal candidates are low-risk STEMI patients who have successfully undergone revascularization and meet specific inclusion criteria.

Not a fit: Patients with significant comorbidities or those unable to manage home monitoring will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to shorter hospital stays and improved patient satisfaction without compromising safety.

How similar studies have performed: While observational studies suggest early discharge is safe for low-risk patients, this randomized controlled trial approach is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Successful revascularisation following STEMI
* Zwolle score \<=3
* No bystander disease awaiting inpatient intervention at the time of screening or consent (so if they have had intervention to a bystander vessel before this they would be eligible)

Exclusion Criteria:

* Haemodynamic instability (Killip class \>I)
* Left ventricular ejection fraction \<45%\<40%
* Sustained ventricular or atrial arrhythmias requiring intervention
* No support at home or social or physical circumstances preventing early discharge
* Unable to use home monitoring equipment
* Unwilling to consent or follow instructions
* Patients visiting from out of our catchment area
* Out-of hospital cardiac arrest
* Patients repatriated to their local hospital within 24 hours
* New or worsening renal failure (i.e. creatinine \>=1.5x baseline)

Where this trial is running

Leeds

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cardiovascular

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.