Early diagnosis of lung cancer in Korean women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-arm prospective pilot study aimed at early lung cancer diagnosis in Korean females aged 45-74 who have never smoked and have a family history of lung cancer. The study will enroll 200 participants over two years, who will undergo low-dose CT (LDCT) screenings and blood draws for plasma-based assays. Participants with positive screening results will receive further diagnostic evaluations, while those with negative results will have repeat LDCT exams for two additional years. A medical history questionnaire will also be administered to assess risk factors.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 45-74 years old
2. Korean female
3. Never smoker defined as a lifetime exposure of less than 100 cigarettes
4. Family history of lung cancer at first degree relatives (parents, siblings, or children)

Exclusion Criteria:

1. Prior history of lung cancer.
2. Diagnosis of any cancer within the past five years
3. Participation in a cancer prevention trial.
4. Present symptoms suggestive of current lung cancer, including: unexplained weight loss of over 5 kilograms within the last 12 months or unexplained hemoptysis.
5. Medical or psychiatric condition precluding informed medical consent.
6. History of LDCT screening, chest CT, PET or PET/CT scan within 10 years

Where it's running

• Samsung Medical Center
  Seoul, Seoul, South Korea Recruiting

Study contacts

• Principal investigator: Um Sang-Won, PhD — Samsung Medical Center
• Study coordinator: Um Sang-Won, PhD
• Email: sangwonum72@gmail.com
• Phone: 82-2-3410-1645

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.