Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Early diagnosis and treatment of gastric cancer using targeted imaging techniques

Official title: Research on Early Diagnosis and Clinical Transformation of Nuclide Probe Based on Bioorthogonal-gastric Cancer Mucin Target Visualization

Run by Peking University Cancer Hospital & Institute · NCT06429891 · Data updated 2026-11-12

This study is testing a new way to find and treat gastric cancer earlier by using special imaging techniques and a targeted antibody that focuses on a specific protein in tumors.

More Solid Tumor trials

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment50 (estimated)
SponsorPeking University Cancer Hospital & Institute
Academic / other
Locations1 site (Beijing, Beijing Municipality)
StatusRecruiting
StartedAugust 20, 2024
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedAugust 22, 2024
Trial IDNCT06429891 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older with histologically confirmed solid tumors and measurable lesions.

Probably not a fit

Patients with significant hepatic or renal dysfunction, or those who are pregnant, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project focuses on the early diagnosis of gastric cancer, which often presents with insidious symptoms leading to late-stage detection. It investigates the characteristics of the tumor microenvironment related to the MUC family of glycoproteins in solid tumors. Utilizing advanced techniques such as immunohistochemistry and gene sequencing, the study aims to develop a specific monoclonal antibody targeting MUC1, which could enhance the detection and treatment of gastric cancer. The approach includes innovative spatial analysis methods to better understand tumor biology and resistance mechanisms.

Why it matters

Potential benefit: If successful, this study could lead to earlier detection and more effective treatment options for patients with gastric cancer.

How similar studies have gone: While similar approaches have been explored, this specific methodology targeting the MUC family in gastric cancer is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Aged ≥18 years old; ECOG 0 or 1;
2. Patients with solid tumor confirmed by histopathology;
3. Patients with imaging confirmed measurable lesions;
4. life expectancy \>=12 weeks.

Exclusion Criteria:

1. Significant hepatic or renal dysfunction;
2. ls pregnant or ready to pregnant;
3. Cannot keep their states for half an hour;
4. Refusal to join the clinical study;
5. Suffering from claustrophobia or other mental diseases;
6. Any other situation that researchers think it is not suitable to participate in the experiment.

Where it's running

  • Beijing Cancer Hospital
    Beijing, Beijing Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.