Early detection of cachexia in gastric cancer patients
Clinical Value of Tumor Cell-derived Exosomal miRNA in Early Diagnosis of Gastric Cancer Cachexia
This study is trying to see if certain tiny particles in the blood can help find cachexia early in people with gastric cancer to improve their treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Xijing Hospital Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT06277986 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the early diagnosis of cachexia in patients with gastric cancer, a condition that significantly impacts treatment outcomes. Researchers are investigating plasma-derived exosomal microRNA (miRNA) as potential biomarkers for early detection of cachexia. The goal is to develop diagnostic kits that can identify cachexia before it becomes clinically significant, thereby improving patient management. The study involves collecting clinical and pathological data from diagnosed gastric cancer patients to support the research.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with gastric cancer who have complete clinical and pathological data.
Not a fit: Patients with multiple tumors, other malignant diseases, or those with chronic wasting and metabolic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier diagnosis and better management of cachexia in gastric cancer patients, potentially improving their treatment outcomes.
How similar studies have performed: While the approach of using miRNA for early diagnosis is promising, it is relatively novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with gastric cancer diagnosed by histopathology or cytopathology 2. Complete clinical and pathological data 3. No previous or current mental illness or disturbance of consciousness Exclusion Criteria: 1. With multiple tumors or other malignant diseases 2. Combined with other chronic wasting and metabolic diseases 3. Past patients with non-tumor cachexia 4. People with mental illness or unable to cooperate
Where this trial is running
Xi'an, Shaanxi
- Fourth Military Medical University — Xi'an, Shaanxi, China (Recruiting)
Study contacts
- Study coordinator: Jipeng Li
- Email: jiangxunliang1992@163.com
- Phone: +86-029-84771533
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.