Early detection and prevention of stomach cancer using endoscopy
Primary Objective: The Primary Objective of the Study is to Evaluate the Acceptability and Feasibility of EGD-SC
This study is testing if using a special camera to look inside the stomach can help find early signs of stomach cancer in people at high risk and see how they feel about this screening.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Sponsor | Rutgers, The State University of New Jersey Academic / other |
| Locations | 2 sites (New Brunswick, New Jersey and 1 other locations) |
| Trial ID | NCT05566899 on ClinicalTrials.gov |
What this trial studies
This study evaluates the feasibility and acceptability of using esophagogastroduodenoscopy (EGD) as a screening tool for early detection and prevention of gastric cancer. It aims to identify pre-cancerous lesions and active Helicobacter pylori infections in a high-risk population, potentially leading to improved survival rates. The study also investigates the time required for EGD during routine colonoscopy and assesses patient attitudes and beliefs regarding gastric cancer screening. By focusing on high-risk groups, the study seeks to understand barriers and motivators for uptake of EGD.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 40 to 80 who are planning to undergo a colonoscopy and have not had an EGD in the last five years.
Not a fit: Patients who have had a total gastrectomy or other anatomical alterations that prevent EGD will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence and mortality of gastric cancer through early detection and intervention.
How similar studies have performed: Other studies have shown promise in using endoscopy for early detection of gastric cancer, but this specific approach is novel in its focus on high-risk populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Have provided signed informed consent for the trial * Aged =40 and =80 years at the time of informed consent * Not planned to undergo EGD and not had EGD in the last five years * Planned to undergo colonoscopy * Half of the recruited subjects will be from high-risk groups * Willing and able to comply with all aspects of the protocol Exclusion Criteria: * Persons with total gastrectomy * Persons with anatomic alteration that precludes EGD * Medical conditions that substantially increase risks for EGD * Had EGD in the last five years
Where this trial is running
New Brunswick, New Jersey and 1 other locations
- Rutgers Cancer Institute of New Jersey — New Brunswick, New Jersey, United States (Recruiting)
- RWJBarnabas Health — New Brunswick, New Jersey, United States (Not_yet_recruiting)
Study contacts
- Principal investigator: Haejin In, MD — Rutgers Cancer Institute of New Jersey
- Study coordinator: Haejin In, MD
- Email: hi80@cinj.rutgers.edu
- Phone: 732-235-3972
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.