Early cardiac rehabilitation after mitral or aortic valve replacement

Phase One Cardiac Rehabilitation Outcomes Post Valve Replacement Surgery

Not applicable Interventional South Valley University · NCT07205393

This study tests whether a supervised early cardiac rehabilitation program helps adults aged 40–60 recover heart and lung function and walking ability after mitral or aortic valve replacement.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages40 Years to 55 Years
SexAll
SponsorSouth Valley University Academic / other
Locations1 site (Qina)
Trial IDNCT07205393 on ClinicalTrials.gov

What this trial studies

In Qena, Egypt, 60 patients aged 40–60 who underwent elective mitral or aortic valve replacement were randomized to a phase one cardiac rehabilitation program or routine postoperative physical therapy. The rehabilitation group received supervised physical exercises and respiratory training while the control group received standard clinic care. Outcomes included oxygen saturation, spirometry measures, and the six-minute walk test, all measured before and after six consecutive weeks of the assigned program. The trial focused on short-term changes in cardiovascular function, pulmonary capacity, and functional ability.

Who should consider this trial

Good fit: Ideal candidates are hemodynamically stable adults aged 40–60 who had elective mitral or aortic valve replacement, can understand and complete measurements, and can provide written informed consent.

Not a fit: Patients with prior ischemic heart disease, severe musculoskeletal disorders, persistent or paroxysmal atrial fibrillation, severe heart failure, uncontrolled arrhythmias, other comorbidities limiting physical activity, or those who had emergency surgery are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, the program could speed recovery and improve cardiovascular and pulmonary function, functional capacity, and quality of life after valve replacement.

How similar studies have performed: Similar cardiac rehabilitation programs have demonstrated benefits after cardiac surgery, although evidence specifically for phase one rehab after valve replacement is more limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The inclusion criteria was elective mitral or aortic valve replacement
* and to be hemodynamically stable to qualify for a structured rehabilitation program.
* Being able to understand and complete measurements.
* And provide informed written consent.

Exclusion Criteria:

* Patient with ischemic heart disease before surgery.
* Those with severe musculoskeletal system disorders.
* Patients who had persistent or paroxysmal atrial fibrillation.
* Individuals with severe heart failure.
* uncontrolled arrhythmias.
* Comorbidity complicating physical activity or other contraindications to phase one cardiac rehabilitation and Patients who underwent an emergency surgical intervention.

Where this trial is running

Qina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Valve Replacement SurgeryCardiac rehabilitationValve replacementSpirometry measures
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.