Dupilumab treatment for children with refractory eosinophilic gastrointestinal disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center observational protocol at Children's Hospital of Fudan University follows children with refractory eosinophilic gastrointestinal disorders who receive standard-dose subcutaneous dupilumab. Investigators will collect symptom measures, endoscopic and histologic findings including eosinophil counts, routine laboratory safety tests, and record adverse events during follow-up. Patients receive licensed dupilumab dosing in a real-world setting rather than an experimental dosing schedule. The goal is to describe clinical response and tolerability in pediatric patients who have not responded to conventional therapies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of Refractory Peptic Ulcers
* with Refractory Eosinophilic Gastrointestinal Disorders

Exclusion Criteria:

* with Active Helicobacter pylori infection at present.
* with Inflammatory bowel disease
* with Parasite infection
* with Cancer

Where it's running

• 201102
  Shanghai, China Recruiting

Study contacts

• Study coordinator: Ying Huang
• Email: yhuang815@163.com
• Phone: 021-64931727

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.