Does THC-COOH appear in sweat after a child’s cannabis intoxication?
Official title: Sudoral Contamination of Young Children Hair During Acute Cannabis Intoxication
Run by University Hospital, Toulouse · NCT07524088 · Data updated 2026-11-12
This study tests whether the cannabis metabolite THC-COOH can be found in sweat after a young child’s cannabis intoxication to see if hair testing is reliable for prior exposure.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 3 Months to 3 Years |
| Sex | All |
| Enrollment | 15 (estimated) |
| Sponsor | University Hospital, Toulouse Academic / other |
| Locations | 1 site (Toulouse) |
| Status | Recruiting |
| Started | July 31, 2026 |
| Main results expected | February 20, 2028 |
| Study ends | April 15, 2028 |
| Registry record updated | September 21, 2026 |
| Trial ID | NCT07524088 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged >3 months and <3 years admitted for acute cannabis intoxication, with parental authorization and appropriate consent.
✕Probably not a fit
Children without detectable cannabinoids in sweat or hair may not benefit from improved interpretation of hair testing.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study investigates the presence of THC-COOH in sweat collected from children under 3 years old who are admitted for acute cannabis intoxication. Sweat is stimulated and analyzed using LC-MS, with hair sampling conducted to compare results. The goal is to determine whether sudoral contamination could confound hair-based exposure assessments and therefore clarify prior exposure history. Follow-up occurs 1–2 months after inclusion to complete the data profile. The study is conducted at pediatric centers in Toulouse and Limoges, led by University Hospital, Toulouse.
Why it matters
Potential benefit: If THC-COOH is not detected in sweat, hair testing may more reliably reflect prior exposure rather than recent contamination.
How similar studies have gone: Adult studies have consistently shown no detectable THC-COOH in sweat, but this pediatric study addresses developmental differences and lacks prior pediatric data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Child admitted to the Specialized Emergency Pole (POSU) and pediatric medico-surgical emergencies for acute cannabis intoxication. * Child older than 3 months and younger than 3 years. * Holders of parental authority, affiliated with or beneficiaries of a social security system. Exclusion Criteria: * History of cannabis intoxication identified during the interview and/or consultation of the medical record. * Contraindication to sweat sampling (described in section 6). * Absence of hair and/or hair length \< 1 cm at the time of inclusion. * Ongoing breastfeeding (exclusive and mixed). * Inability to provide study-related informations to the holders of parental authority.
Where it's running
-
Centre Hospitalier Universitaire
Toulouse, France Recruiting
Study contacts
- Principal investigator: Thomas Lanot — University Hospital of Toulouse
- Study coordinator: Nadège Algans
- Email: algans.n@chu-toulouse.fr
- Phone: 0561777204
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.