Clinical trial Recruiting at 1 site Interventional Ages 3 Months to 3

Does THC-COOH appear in sweat after a child’s cannabis intoxication?

Official title: Sudoral Contamination of Young Children Hair During Acute Cannabis Intoxication

Run by University Hospital, Toulouse · NCT07524088 · Data updated 2026-11-12

This study tests whether the cannabis metabolite THC-COOH can be found in sweat after a young child’s cannabis intoxication to see if hair testing is reliable for prior exposure.

Quick facts

Study typeInterventional
Ages3 Months to 3 Years
SexAll
Enrollment15 (estimated)
SponsorUniversity Hospital, Toulouse
Academic / other
Locations1 site (Toulouse)
StatusRecruiting
StartedJuly 31, 2026
Main results expectedFebruary 20, 2028
Study endsApril 15, 2028
Registry record updatedSeptember 21, 2026
Trial IDNCT07524088 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Children aged >3 months and <3 years admitted for acute cannabis intoxication, with parental authorization and appropriate consent.

Probably not a fit

Children without detectable cannabinoids in sweat or hair may not benefit from improved interpretation of hair testing.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study investigates the presence of THC-COOH in sweat collected from children under 3 years old who are admitted for acute cannabis intoxication. Sweat is stimulated and analyzed using LC-MS, with hair sampling conducted to compare results. The goal is to determine whether sudoral contamination could confound hair-based exposure assessments and therefore clarify prior exposure history. Follow-up occurs 1–2 months after inclusion to complete the data profile. The study is conducted at pediatric centers in Toulouse and Limoges, led by University Hospital, Toulouse.

Why it matters

Potential benefit: If THC-COOH is not detected in sweat, hair testing may more reliably reflect prior exposure rather than recent contamination.

How similar studies have gone: Adult studies have consistently shown no detectable THC-COOH in sweat, but this pediatric study addresses developmental differences and lacks prior pediatric data.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Child admitted to the Specialized Emergency Pole (POSU) and pediatric medico-surgical emergencies for acute cannabis intoxication.
* Child older than 3 months and younger than 3 years.
* Holders of parental authority, affiliated with or beneficiaries of a social security system.

Exclusion Criteria:

* History of cannabis intoxication identified during the interview and/or consultation of the medical record.
* Contraindication to sweat sampling (described in section 6).
* Absence of hair and/or hair length \< 1 cm at the time of inclusion.
* Ongoing breastfeeding (exclusive and mixed).
* Inability to provide study-related informations to the holders of parental authority.

Where it's running

  • Centre Hospitalier Universitaire
    Toulouse, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.