Disseminated Lyme and Borrelia miyamotoi infections after anti‑CD20 treatment in France

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter, real‑life observational effort led by CHU Strasbourg compiles clinical, biological, radiological, and pharmacological data on cases of disseminated Borrelia burgdorferi sensu lato or Borrelia miyamotoi occurring after anti‑CD20 monoclonal antibody therapy. Eligible cases require molecular confirmation of disseminated borreliosis occurring within 24 months of anti‑CD20 treatment given between January 1, 2010 and July 30, 2025. Data will be extracted from hospital records and laboratory results and centrally analyzed to describe presentations, diagnostic pathways, treatments, and outcomes. No experimental treatments are administered as part of the project; it is purely observational and descriptive.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Minor or adult subject
* Having presented disseminated borreliosis confirmed by molecular biology (Borrelia burgdorferi sl. or Borrelia miyamotoi) within 24 months of receiving treatment with an anti-CD20 monoclonal antibody between January 1, 2010, and July 30, 2025.

Exclusion Criteria:

\- Refusal to participate in the study

Where it's running

• Laboratoire de Bactériologie - CHU de Strasbourg - France
  Strasbourg, France Recruiting

Study contacts

• Study coordinator: Pierre BOYER, MD
• Email: pierre.boyer@chru-strasbourg.fr
• Phone: 33 3 69 55 14 69

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.