Digital training to improve optical diagnosis of colorectal polyps
Impact of a Digital Training Program (Colo-ID) on Optical Histologic Prediction and Management of Colorectal Polyps: A Prospective Study
Clinique Paris-Bercy · NCT07424391
This project will test whether a digital training app helps doctors more accurately predict polyp tissue type during colonoscopy for adults who have polyps.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Clinique Paris-Bercy (other) |
| Locations | 1 site (Charenton-le-Pont, Val de Marne) |
| Trial ID | NCT07424391 on ClinicalTrials.gov |
What this trial studies
COLO-PREDICT is a prospective, single-center observational study examining whether a structured digital training program (Colo-ID) improves real-world optical histology predictions of colorectal polyps. Adult patients having a colonoscopy with at least one detected polyp are consecutively included and the endoscopist records an optical prediction for each polyp during the procedure. All polyps are removed per routine care and sent for histopathology, which serves as the reference standard to compare against the recorded optical predictions. The study does not change patient management or surveillance intervals and aims to measure diagnostic accuracy before and after the training intervention in everyday clinical practice.
Who should consider this trial
Good fit: Adults (age 18 or older) undergoing colonoscopy at the participating center who have at least one colorectal polyp detected and a recorded optical prediction are eligible.
Not a fit: People without any polyps at colonoscopy, patients under 18, or anyone whose polyp histology is not available will not benefit from the study findings directly.
Why it matters
Potential benefit: If successful, the program could help clinicians more accurately identify polyp type during colonoscopy, potentially reducing unnecessary pathology testing and streamlining follow-up decisions.
How similar studies have performed: Prior research has shown that targeted training and enhanced imaging can improve optical diagnosis performance, but variability remains and digital, app-based training approaches are relatively new.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged ≥18 years * Patients undergoing colonoscopy in routine clinical practice at the participating center * At least one colorectal polyp detected during colonoscopy * Optical histology prediction recorded during the procedure * Histopathological analysis available for resected polyps (reference standard) Exclusion Criteria: * Patients aged \<18 years * Refusal/opposition to use of data (if applicable under local regulations) * Missing key study data (e.g., no recorded optical prediction or no histopathology result)
Where this trial is running
Charenton-le-Pont, Val de Marne
- Clinique Paris-Bercy — Charenton-le-Pont, Val de Marne, France (RECRUITING)
Study contacts
- Principal investigator: David D Karsenti — Centre d'Explorations Digestives
- Study coordinator: David Karsenti, MD
- Email: karsenti.paris@gmail.com
- Phone: +33145486565
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Colorectal Polyps, Optical diagnosis, Colonoscopy, Histologic prediction, Resect-and-discard strategy, Digital training, Endoscopic imaging, Polyp characterization