Digital tools to help youth seek care sooner when at risk for psychosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The project creates a Digital Laboratory that uses Mental Health America's national online screening to identify 25,000 youth ages 12–29 who screen positive for psychosis risk and to define help-seeking subtypes. It will use Micro-Randomized Trials and a Sequential Multiple Assignment Randomized Trial (SMART) to iteratively develop and optimize personalized digital nudges and engagement strategies. The team will identify the most accurate online screening threshold for clinical high risk (CHR) and connect indicated youth to local AMP-SCZ clinical programs across the U.S. through an academic–industry partnership that includes Columbia, UCSF, UCD, Mental Health America, and other collaborators.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ages 12-29 years
* Living within a 50-mile radius of a US based AMP-SCZ site
* Able to complete the English language PQ-B on MHA's screening platform

Where it's running

• Columbia University Irving Medical Center
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Michael Birnbaum, MD — Columbia University
• Study coordinator: Michael Birnbaum, MD
• Email: mlb2216@cumc.columbia.edu
• Phone: 212-523-2154

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Digital strategies to improve help-seeking for youth at risk of psychosis

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• State Representation in Early Psychosis 2

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• On Track for Wellness: a stepped-wedge program to boost sleep and activity in first-episode psychosis

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• Adding ketones to antipsychotics in young adults with first episode psychosis

  This study tests whether giving exogenous ketones on top of antipsychotic treatment helps young adults experiencing a first episode of psychosis.

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• Add CBD to antipsychotic treatment for first-episode psychosis to see if it helps more than placebo

  This study tests whether adding cannabidiol (CBD) to ongoing antipsychotic treatment helps people with a first episode of psychosis who haven’t fully responded to their first antipsychotic, compared with a placebo.

  Recruiting at 2 sites Phase 3 University of Oxford · Vienna and 16 other locations · NCT06778564

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.