Digital mirror therapy versus conventional mirror therapy for arm recovery after stroke
Official title: Digital Mirror Therapy in Poststroke Rehabilitation: Efficacy and Patient-reported Facilitators and Barriers to Adherence.
Run by The Hong Kong Polytechnic University · NCT07460128 · Data updated 2026-11-12
This test will see if a digital mirror therapy program helps adults with chronic stroke improve arm movement more than conventional mirror therapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 44 (estimated) |
| Sponsor | The Hong Kong Polytechnic University Academic / other |
| Locations | 2 sites (Hong Kong and 1 other locations) |
| Status | Recruiting |
| Started | March 2, 2026 |
| Main results expected | December 31, 2028 |
| Study ends | December 31, 2028 |
| Registry record updated | March 10, 2026 |
| Trial ID | NCT07460128 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 18–80 who are at least six months post-ischemic or hemorrhagic stroke with residual upper limb impairment (Functional Test for Hemiplegic Extremity Hong Kong levels 2–6) and who can communicate and follow instructions.
✕Probably not a fit
Patients with severe spasticity (Modified Ashworth Scale >2), notable cognitive impairment (Abbreviated Mental Test - Hong Kong score <6), other neurologic diseases, or inability to express thoughts are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, parallel-group, assessor-blinded trial compares an augmented-reality, computer-vision–enabled digital mirror therapy program with conventional mirror therapy for upper limb rehabilitation in people more than six months after stroke. Participants aged 18–80 with moderate residual upper limb dysfunction will be randomized to receive either digital or conventional mirror therapy and followed for clinical motor outcomes and community integration. The study will also measure musculoskeletal physiology by recording upper-extremity muscle co-activation patterns and collect patient-reported barriers and facilitators to using the digital system. Exclusion criteria include other neurologic diseases, significant cognitive impairment, severe spasticity, or inability to communicate effectively.
Why it matters
Potential benefit: If successful, the digital approach could lead to greater arm function recovery and better participation in daily life by increasing engagement and sensory feedback during therapy.
How similar studies have gone: Conventional mirror therapy has strong evidence for poststroke arm recovery, while small pilot studies of digital or augmented mirror systems report promising engagement and functional signals but lack large randomized comparisons.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. diagnosis of ischemic or hemorrhagic stroke more than 6 months; 2. age between 18 and 80 years; 3. upper limb function rated at levels 2-6 according to the Functional Test for Hemiplegic Extremity Hong Kong Version Exclusion Criteria: 1. any concomitant neurological disease other than stroke; 2. signs of cognitive impairment, defined as a score below 6 out of 10 on the Abbreviated Mental Test - Hong Kong Version ; 3. or severe spasticity in the hemiparetic upper extremity muscles, with a Modified Ashworth Scale score greater than 2; 4. unable to express thoughts effectively through verbal speech or written language.
Where it's running
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Hong Kong Polytechnic University
Hong Kong, Hong Kong Recruiting -
Hong Kong Polytechnic University
Hong Kong, Hong Kong Recruiting
Study contacts
- Principal investigator: Jack Jiaqi Zhang — The Hong Kong Polytechnic University
- Study coordinator: Jack Jiaqi Zhang, PhD
- Email: jack-jiaqi.zhang@polyu.edu.hk
- Phone: 27666696
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.