Clinical trial Recruiting at 2 sites Interventional Ages 18 to 80

Digital mirror therapy versus conventional mirror therapy for arm recovery after stroke

Official title: Digital Mirror Therapy in Poststroke Rehabilitation: Efficacy and Patient-reported Facilitators and Barriers to Adherence.

Run by The Hong Kong Polytechnic University · NCT07460128 · Data updated 2026-11-12

This test will see if a digital mirror therapy program helps adults with chronic stroke improve arm movement more than conventional mirror therapy.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment44 (estimated)
SponsorThe Hong Kong Polytechnic University
Academic / other
Locations2 sites (Hong Kong and 1 other locations)
StatusRecruiting
StartedMarch 2, 2026
Main results expectedDecember 31, 2028
Study endsDecember 31, 2028
Registry record updatedMarch 10, 2026
Trial IDNCT07460128 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults 18–80 who are at least six months post-ischemic or hemorrhagic stroke with residual upper limb impairment (Functional Test for Hemiplegic Extremity Hong Kong levels 2–6) and who can communicate and follow instructions.

Probably not a fit

Patients with severe spasticity (Modified Ashworth Scale >2), notable cognitive impairment (Abbreviated Mental Test - Hong Kong score <6), other neurologic diseases, or inability to express thoughts are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, parallel-group, assessor-blinded trial compares an augmented-reality, computer-vision–enabled digital mirror therapy program with conventional mirror therapy for upper limb rehabilitation in people more than six months after stroke. Participants aged 18–80 with moderate residual upper limb dysfunction will be randomized to receive either digital or conventional mirror therapy and followed for clinical motor outcomes and community integration. The study will also measure musculoskeletal physiology by recording upper-extremity muscle co-activation patterns and collect patient-reported barriers and facilitators to using the digital system. Exclusion criteria include other neurologic diseases, significant cognitive impairment, severe spasticity, or inability to communicate effectively.

Why it matters

Potential benefit: If successful, the digital approach could lead to greater arm function recovery and better participation in daily life by increasing engagement and sensory feedback during therapy.

How similar studies have gone: Conventional mirror therapy has strong evidence for poststroke arm recovery, while small pilot studies of digital or augmented mirror systems report promising engagement and functional signals but lack large randomized comparisons.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. diagnosis of ischemic or hemorrhagic stroke more than 6 months;
2. age between 18 and 80 years;
3. upper limb function rated at levels 2-6 according to the Functional Test for Hemiplegic Extremity Hong Kong Version

Exclusion Criteria:

1. any concomitant neurological disease other than stroke;
2. signs of cognitive impairment, defined as a score below 6 out of 10 on the Abbreviated Mental Test - Hong Kong Version ;
3. or severe spasticity in the hemiparetic upper extremity muscles, with a Modified Ashworth Scale score greater than 2;
4. unable to express thoughts effectively through verbal speech or written language.

Where it's running

  • Hong Kong Polytechnic University
    Hong Kong, Hong Kong
    Recruiting
  • Hong Kong Polytechnic University
    Hong Kong, Hong Kong
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.