Digital meditation intervention for emotional well-being in lonely older adults

Dynamic Neural Systems Underlying Social-emotional Functions in Older Adults

Not applicable Interventional University of California, San Francisco · NCT05645835

This study tests whether a digital meditation program can improve the emotional well-being of lonely older adults by comparing their experiences with those who are not using the program.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment75 (estimated)
Ages60 Years to 120 Years
SexAll
SponsorUniversity of California, San Francisco Academic / other
Locations1 site (San Francisco, California)
Trial IDNCT05645835 on ClinicalTrials.gov

What this trial studies

This study assesses the effects of a remote, app-delivered digital meditation intervention on the emotional well-being of lonely older adults. Participants will undergo neuroimaging and electrophysiological assessments while engaging in the intervention and watching an awe-inspiring movie. The study aims to explore the neural correlates of emotional responses and social interactions through fMRI and EEG measurements. A waitlist control group will be used to compare outcomes between those receiving the intervention and those not receiving it.

Who should consider this trial

Good fit: Ideal candidates are cognitively healthy adults aged 60 and older who are fluent in English and have little to no prior meditation experience.

Not a fit: Patients with severe psychiatric or neurological disorders, active meditators, or those with MRI contraindications may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve emotional well-being and reduce feelings of loneliness in older adults.

How similar studies have performed: Other studies have shown promising results with digital interventions for emotional well-being, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 60 years of age or older
* English language fluency
* Naive to meditation practices (not actively meditating more than one hour per month and/or meditation practice for less than a year in their entire life-time)
* No MRI contra-indications
* Cognitively healthy (no diagnosis of dementia, stroke, developmental disorders, or major systemic diseases that may impact cognitive function)

Exclusion Criteria:

* Below 60 years of age
* Not fluent in English
* Active meditator (meditating more than one hour per month and/or meditation practice for more than a year in their entire life-time).
* Presence of a severe psychiatric (e.g. schizophrenia, bipolar disorder, PTSD), neurological (epilepsy, traumatic brain injury, dementia, multiple sclerosis), or developmental disorder (e.g. autism)
* Systemic disease (e.g. major recent surgeries, cancer)
* Claustrophobia
* Contraindications for MR safety (e.g. metal in body, cochlea implants)

Where this trial is running

San Francisco, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions LonelinessOlder AdultsfMRIEmotionsEEGDigital InterventionMeditation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.