Dietary intervention to improve health for night shift workers
Dietary Intervention to Mitigate Adverse Consequences of Night Work
This study is testing if a special diet can help night shift workers improve their health and manage the challenges that come with working at odd hours.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Brigham and Women's Hospital Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Trial ID | NCT04868526 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of a dietary intervention designed to mitigate the negative health impacts associated with night shift work. Participants will undergo two inpatient stays where they will receive identical meals while their metabolic responses are closely monitored through frequent blood draws and various biological sample collections. The study focuses on addressing the metabolic health challenges faced by shift workers due to circadian misalignment, with the goal of developing evidence-based dietary strategies to improve their health outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 18-45 with a BMI between 20.0 and 29.9 of European, Hispanic, or African-American ancestry.
Not a fit: Patients with acute or chronic medical conditions, or those with a history of substance dependency or psychiatric disorders, may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve metabolic health and reduce the risk of diabetes among night shift workers.
How similar studies have performed: While the specific dietary intervention for night shift workers is novel, similar studies addressing metabolic health in shift workers have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-45 yr old * BMI 20.0-29.9 * European/Hispanic/African-American ancestry * No acute, chronic or debilitating medical conditions (e.g. metabolic, cardiovascular, respiratory, neurological, cancers, etc.) Exclusion Criteria: * Currently smoking/vaping or 5 or more years of smoking/vaping * History of drug or alcohol dependency * History of psychiatric illness or disorder
Where this trial is running
Boston, Massachusetts
- Brigham and Women's Hospital — Boston, Massachusetts, United States (Recruiting)
Study contacts
- Principal investigator: Frank Scheer, PhD — Brigham and Women's Hospital
- Study coordinator: Megan Munn
- Email: mmunn@bwh.harvard.edu
- Phone: 6175258259
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.