Dietary approaches to improve asthma control

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot trial investigates the impact of three different dietary interventions on asthma control and lung function in adults with asthma. Participants will be randomly assigned to follow a DGA Diet, MCT Diet, or KETO Diet for seven days, with a washout period in between each diet. The study aims to assess changes in asthma control and lung function after each dietary phase, while also exploring factors that may influence dietary response. A total of 15 adults will be recruited for this crossover design trial.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: 18-65 years
* BMI: 18.5 - 29.99 kg/m2
* asthma diagnosed by medical specialist (confirmed in medical history)
* partly controlled or uncontrolled asthma by Asthma Control Test score ≤22
* owns a device compatible with ZEPHYRx platform
* stable asthma medication use (no change in the past 2 months).

Exclusion Criteria:

* Diabetes or using diabetes medications that may lower blood glucose levels
* point of care fasting blood glucose ≥126 mg/dl or triglycerides ≥400 mg/dl
* current smoking or smoking history of greater than 10 pack-years
* other significant respiratory or cardiac disease or the presence of clinically important comorbidities, e.g., COPD, renal failure, liver disease; uncontrolled hypertension defined as systolic blood pressure ≥160 mm/Hg, or diastolic blood pressure ≥100 mm/Hg
* pregnant or nursing women
* food preferences or allergies inconsistent with study diet capabilities
* noncompliance with lead-in period requirements.

Where it's running

• Pennington Biomedical Research Center
  Baton Rouge, Louisiana, United States Recruiting

Study contacts

• Principal investigator: Jacob T Mey, PhD, RD — Pennington Biomedical Research Center
• Study coordinator: Jacob T Mey, PhD, RD
• Email: jacob.mey@pbrc.edu
• Phone: 225-763-2644

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.