Dietary approaches to improve asthma control
Individualized Nutrition to Help Asthmatics Improve Lung Function and Energetics (INHALE)
This study is testing whether different diets can help adults with asthma breathe better and manage their symptoms.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 15 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Pennington Biomedical Research Center Academic / other |
| Locations | 1 site (Baton Rouge, Louisiana) |
| Trial ID | NCT06151405 on ClinicalTrials.gov |
What this trial studies
This pilot trial investigates the impact of three different dietary interventions on asthma control and lung function in adults with asthma. Participants will be randomly assigned to follow a DGA Diet, MCT Diet, or KETO Diet for seven days, with a washout period in between each diet. The study aims to assess changes in asthma control and lung function after each dietary phase, while also exploring factors that may influence dietary response. A total of 15 adults will be recruited for this crossover design trial.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 with partly controlled or uncontrolled asthma and a stable medication regimen.
Not a fit: Patients with diabetes, significant comorbidities, or those with dietary restrictions incompatible with the study diets may not benefit.
Why it matters
Potential benefit: If successful, this study could provide new dietary strategies to improve asthma management and enhance lung function.
How similar studies have performed: While dietary interventions in asthma management are being explored, this specific crossover approach is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age: 18-65 years * BMI: 18.5 - 29.99 kg/m2 * asthma diagnosed by medical specialist (confirmed in medical history) * partly controlled or uncontrolled asthma by Asthma Control Test score ≤22 * owns a device compatible with ZEPHYRx platform * stable asthma medication use (no change in the past 2 months). Exclusion Criteria: * Diabetes or using diabetes medications that may lower blood glucose levels * point of care fasting blood glucose ≥126 mg/dl or triglycerides ≥400 mg/dl * current smoking or smoking history of greater than 10 pack-years * other significant respiratory or cardiac disease or the presence of clinically important comorbidities, e.g., COPD, renal failure, liver disease; uncontrolled hypertension defined as systolic blood pressure ≥160 mm/Hg, or diastolic blood pressure ≥100 mm/Hg * pregnant or nursing women * food preferences or allergies inconsistent with study diet capabilities * noncompliance with lead-in period requirements.
Where this trial is running
Baton Rouge, Louisiana
- Pennington Biomedical Research Center — Baton Rouge, Louisiana, United States (Recruiting)
Study contacts
- Principal investigator: Jacob T Mey, PhD, RD — Pennington Biomedical Research Center
- Study coordinator: Jacob T Mey, PhD, RD
- Email: jacob.mey@pbrc.edu
- Phone: 225-763-2644
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.