Diagnosis and treatment of drug-resistant focal epilepsies

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on patients with drug-resistant focal epilepsy, a condition where seizures are not adequately controlled by medication. It aims to evaluate the effectiveness of surgical interventions, specifically the ablation of the epileptogenic zone, in improving patient outcomes. The study will involve careful selection of candidates based on their medical history and neuroimaging results. By analyzing the results of surgical treatment, the study seeks to provide insights into the potential for achieving seizure freedom in these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients with focal epilepsy, long history of drug-resistant seizures, on mono- or polypharmacy antiepileptic therapy affected by known epileptogenic lesion or without lesions evident on neuroimaging investigations (cryptogenic). - - - Patients with recent onset of focal seizures, in mono- or polypharmacy, with controlled or rare seizures, or still in the absence of antiepileptic therapy affected by neoplastic lesion.

Exclusion Criteria:

* Patients in whom the diagnosis of epilepsy is doubtful. Patients with cognitive or psychiatric disorders that prevent participation in an interview, proper understanding of informed consent, or completion of questionnaires.

Where it's running

• Foundation IRCCS Carlo Besta Neurological Institute
  Milan, Italy Recruiting

Study contacts

• Study coordinator: Marco De Curtis, M.D.
• Email: marco.decurtis@istituto-besta.it
• Phone: 02.2394.2242

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.