Development of a quality of life tool for post-COVID-19 patients

Post Acute COVID-19 Quality of Life (PAC-19QoL) Tool Development and Patient Registry (PAC-19QoLReg)

Observational Medialis Ltd. · NCT04586413

This study is trying to create a new tool to measure how COVID-19 affects the quality of life for people recovering from the virus, including those who were hospitalized and those who weren't.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorMedialis Ltd. Industry-sponsored
Locations1 site (Oxford)
Trial IDNCT04586413 on ClinicalTrials.gov

What this trial studies

This observational study aims to develop a specific quality of life measure for individuals recovering from COVID-19. Participants will be recruited and divided into three groups based on their hospitalization status: not hospitalized, hospitalized but not in intensive care, and hospitalized in intensive care. The study will utilize a novel method to gather insights from participants about the areas of their lives affected by COVID-19, which will inform the creation of the quality of life tool. Following the development phase, participants will be invited to complete the tool monthly for a year to assess its effectiveness.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have had a confirmed COVID-19 infection or antibody test.

Not a fit: Patients who have not been diagnosed with COVID-19 or are under 18 years old may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a tailored quality of life measure that better reflects the experiences of post-COVID-19 patients.

How similar studies have performed: While there have been studies on quality of life in COVID-19 patients, the specific approach of developing a patient-reported measure based on direct input from patients is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Phase One

Inclusion Criteria:

* The participant has had either a confirmed COVID-19 test while infected or a confirmed COVID-19 antibody test post-infection
* The participant is aged 18 years or older
* The participant is capable of providing informed consent
* The participant can read, write and converse in English
* The participant can comply with the study schedule

Exclusion Criteria:

* The participant does not have a confirmed COVID-19 test or antibody test
* The participant is aged under 18 years
* The participant is not capable of giving informed consent
* The participant is unable to read, write and converse in English
* The participant is unable to comply with study schedule data collection

Phase Two

Inclusion Criteria:

* The participant has had either a confirmed COVID-19 test while infected or a confirmed COVID-19 antibody test post-infection or a clinical diagnosis of COVID-19
* The participant is aged 18 years or older
* The participant is capable of providing informed consent
* The participant can read, write and converse in English
* The participant can comply with the study schedule

Exclusion Criteria:

* The participant does not have a confirmed COVID-19 test or antibody test or clinical diagnosis of COVID-19
* The participant is aged under 18 years
* The participant is not capable of giving informed consent
* The participant is unable to read, write and converse in English
* The participant is unable to comply with study schedule data collection

Where this trial is running

Oxford

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Covid19Quality of LifePost-Covid19
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.