Developing organoids from breast cancer tissue

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a living biobank of breast cancer organoids derived from patient tissue samples collected during routine surgical procedures. By obtaining small samples of excised tumors and blood for genetic analysis, the study seeks to understand how these organoids reflect disease progression, treatment response, and relapse across different breast cancer subtypes. The goal is to develop a patient-tailored clinical model that addresses tumor heterogeneity and guides individualized treatment selection without altering the standard care process for participants.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female,
* \>18 years,
* Family Anamneses
* Breast cancer (proven by histopathology), Included subtypes; (ER-,PR- HER2-); (ER+, PR+, HER2-); (ER+, PR+ HER2+).
* Primary surgery (lumpectomy or mastectomy)

Exclusion Criteria:

\- Physically or mentally incapable or incompetent to sign informed consent

Where it's running

• Maastricht University Medical Center
  Maastricht, Netherlands Recruiting

Study contacts

• Principal investigator: Marc Vooijs, PhD — Maastricht University
• Study coordinator: Chantal Overhof
• Email: chantal.overhof@maastro.nl
• Phone: +31 88 44 55 683

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.