Developing MRI protocols and neuro-physiological measurements
Official title: Development of MRI Protocols and Associated Neuro-physiological Explorations in Healthy and Pathological Subjects
Run by University Hospital, Grenoble · NCT05036629 · Data updated 2026-11-12
This study is testing new MRI techniques to see if they can create better images and measurements for both healthy people and patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | University Hospital, Grenoble Academic / other |
| Locations | 1 site (La Tronche) |
| Status | Recruiting |
| Started | September 9, 2021 |
| Main results expected | September 8, 2031 |
| Study ends | September 8, 2031 |
| Registry record updated | October 2, 2026 |
| Trial ID | NCT05036629 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include healthy individuals and patients undergoing follow-up at the CHU with conditions relevant to the research protocol.
✕Probably not a fit
Patients with contraindications to MRI procedures, such as those with metallic implants or severe claustrophobia, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project focuses on enhancing MRI technology by optimizing sequence parameters and designing stimulation paradigms for both healthy individuals and patients. The aim is to improve the quality and relevance of MRI images while considering anatomical, functional, and metabolic parameters. Participants will undergo MRI scans and additional physiological measurements to assess the effectiveness of the new protocols. The study will ensure that all procedures are conducted with informed consent and adherence to safety protocols.
Why it matters
Potential benefit: If successful, this study could lead to improved MRI imaging techniques that enhance diagnostic accuracy for various neurological conditions.
How similar studies have gone: While there have been advancements in MRI technology, this specific approach to optimizing protocols and physiological measurements is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants with normal or corrected vision * Participants affiliated to a social security scheme or beneficiaries of such a scheme * Participants with French as their mother tongue * Participants who have given the signed informed consent before carrying out any procedure related to the study. * Volunteer patients will be recruited as part of their follow-up at the CHU. Their pathology will be in agreement with that of the research protocol to be optimized. Exclusion Criteria: Criteria relating to contraindications to the explorations provided for by the MRI protocol: * metallic glitter in the eyes * retinal operation * claustrophobia * wearer of pacemaker or cardiac defribrillator or vascular clip or prosthesis cardiac or insulin pump or implanted device to deliver medication or hearing implant or prosthesis or vascular shunt or paragraph or screws, plate metal or tattoo or piercing or implanted metal object or lead shot hunt * Alcohol ingestion before the examination * Pregnant, lactating and parturient women * Major protected by law * Participants under administrative or judicial supervision * Participation in another ongoing study if the study may interfere with participation in the protocol MAP-IRMaGe.
Where it's running
-
Unité Mixte de Service IRMaGe US 017
La Tronche, France Recruiting
Study contacts
- Study coordinator: ATTYE ARNAUD, MD, PhD
- Email: aattye@chu-grenoble-alpes.fr
- Phone: 4 76 76 57 39
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.