Developing MRI protocols and neuro-physiological measurements
Development of MRI Protocols and Associated Neuro-physiological Explorations in Healthy and Pathological Subjects
This study is testing new MRI techniques to see if they can create better images and measurements for both healthy people and patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 600 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Grenoble Academic / other |
| Locations | 1 site (La Tronche) |
| Trial ID | NCT05036629 on ClinicalTrials.gov |
What this trial studies
This project focuses on enhancing MRI technology by optimizing sequence parameters and designing stimulation paradigms for both healthy individuals and patients. The aim is to improve the quality and relevance of MRI images while considering anatomical, functional, and metabolic parameters. Participants will undergo MRI scans and additional physiological measurements to assess the effectiveness of the new protocols. The study will ensure that all procedures are conducted with informed consent and adherence to safety protocols.
Who should consider this trial
Good fit: Ideal candidates include healthy individuals and patients undergoing follow-up at the CHU with conditions relevant to the research protocol.
Not a fit: Patients with contraindications to MRI procedures, such as those with metallic implants or severe claustrophobia, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved MRI imaging techniques that enhance diagnostic accuracy for various neurological conditions.
How similar studies have performed: While there have been advancements in MRI technology, this specific approach to optimizing protocols and physiological measurements is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants with normal or corrected vision * Participants affiliated to a social security scheme or beneficiaries of such a scheme * Participants with French as their mother tongue * Participants who have given the signed informed consent before carrying out any procedure related to the study. * Volunteer patients will be recruited as part of their follow-up at the CHU. Their pathology will be in agreement with that of the research protocol to be optimized. Exclusion Criteria: Criteria relating to contraindications to the explorations provided for by the MRI protocol: * metallic glitter in the eyes * retinal operation * claustrophobia * wearer of pacemaker or cardiac defribrillator or vascular clip or prosthesis cardiac or insulin pump or implanted device to deliver medication or hearing implant or prosthesis or vascular shunt or paragraph or screws, plate metal or tattoo or piercing or implanted metal object or lead shot hunt * Alcohol ingestion before the examination * Pregnant, lactating and parturient women * Major protected by law * Participants under administrative or judicial supervision * Participation in another ongoing study if the study may interfere with participation in the protocol MAP-IRMaGe.
Where this trial is running
La Tronche
- Unité Mixte de Service IRMaGe US 017 — La Tronche, France (Recruiting)
Study contacts
- Study coordinator: ATTYE ARNAUD, MD, PhD
- Email: aattye@chu-grenoble-alpes.fr
- Phone: 4 76 76 57 39
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.