Developing advanced MRI techniques for understanding human body composition and function
Development and Validation of Multi-nuclear Magnetic Resonance Imaging and Spectroscopy for Whole Body Human Applications
AdventHealth Translational Research Institute · NCT02663362
This study is testing new MRI techniques to see how well they can help us understand the makeup and function of the human body.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 12 Years to 89 Years |
| Sex | All |
| Sponsor | AdventHealth Translational Research Institute (other) |
| Locations | 1 site (Orlando, Florida) |
| Trial ID | NCT02663362 on ClinicalTrials.gov |
What this trial studies
This study aims to develop and refine multi-nuclear magnetic resonance imaging and spectroscopy techniques to better understand the composition and function of the human body. It focuses on evaluating the reproducibility of acquiring multi-nuclear data using a new 3T Philips Magnet. Participants will undergo imaging procedures to assess how these advanced techniques can provide insights into body composition and function. The study is observational and does not involve any treatment interventions.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy individuals aged 12 to 89 who can comply with the imaging procedures and have no contraindications for MRI.
Not a fit: Patients with internal metal medical devices or those who are claustrophobic may not benefit from this study due to the nature of MRI procedures.
Why it matters
Potential benefit: If successful, this study could enhance diagnostic capabilities and improve understanding of various health conditions related to body composition and function.
How similar studies have performed: While the use of MRI and spectroscopy is well-established, the specific application of multi-nuclear techniques for whole-body assessments is relatively novel and may not have been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female * Age 12 - 89 * Healthy (self assessed) * Weight under 350lbs * Able to walk 50 yards without stopping * Able to travel to hospital for study visits * Able to follow a 3-step command * Able to remain in Magnetic Resonance (MR) scanner for up to 2 hours Exclusion Criteria: * Have internal metal medical devices, including cardiac pacemakers, aortic or cerebral aneurysm clips, artificial heart valves, ferromagnetic implants, shrapnel, wire sutures, joint replacements, bone or joint pins/rods/screws, metal fragments in your eye, or non-removable jewelry such as rings. * Are unwilling or unable to complete the imaging procedures for the duration of the MRI scan due to claustrophobia or other reason. * Serious mental illness that might preclude subject's ability to comply with study treatment * Life expectancy of less than 1 year * Are pregnant or plan on becoming pregnant in the next 8 weeks.
Where this trial is running
Orlando, Florida
- Translational Research Institute for Metabolism and Diabetes — Orlando, Florida, United States (RECRUITING)
Study contacts
- Principal investigator: Heather Cornnell, PhD — Translational Research Institute for Metabolism and Diabetes
- Study coordinator: Recruitment Department
- Email: tri@flhosp.org
- Phone: 407-303-7100
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Human Body Composition, Human Body Function, magnetic resonance imaging, magnetic resonance spectroscopy