Developing a system to support clinical decisions for severe polytrauma patients
Разработка системы поддержки принятия клинических решений для тяжелых больных с политравмой
This study is trying to create a system that helps doctors make better decisions for patients with severe injuries in their first day of care to see if it can improve their chances of recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 28 Years and up |
| Sex | All |
| Sponsor | Semey State Medical University Academic / other |
| Locations | 1 site (Semey, Abai) |
| Trial ID | NCT06323096 on ClinicalTrials.gov |
What this trial studies
This observational study aims to create a Clinical Decision Support System (CDSS) for managing severe polytrauma patients during their early inpatient care. It seeks to predict various complications such as systemic inflammatory response syndrome, significant blood loss, acute traumatic coagulopathy, pneumonia, and overall patient outcomes within the first 24 hours of admission. The study will collect both retrospective and prospective data from multiple clinics that provide trauma care, ensuring a diverse patient population. By analyzing this data, the study hopes to improve decision-making and potentially reduce mortality and adverse outcomes in these patients.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who meet specific criteria for polytrauma as defined by the new Berlin definition.
Not a fit: Patients who refuse to participate, die shortly after hospitalization, or have incomplete medical records may not benefit from this study.
Why it matters
Potential benefit: If successful, this system could significantly enhance the management and outcomes of patients with severe polytrauma.
How similar studies have performed: While the approach of developing a CDSS for polytrauma patients is innovative, similar systems in other medical fields have shown promise in improving patient outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Availability of informed consent, signed by the patient or his legal representative; * Patients over 18 years of age; * Expanded criteria of the new Berlin definition of polytrauma: patients who comply with three conditions: 1. Presence of damage to one area of the body with an AIS score ≥3 points. 2. Presence of damage to ≥2 areas of the body with an AIS score of ≥2. 3. Presence of ≥1 physiological risk factors and/or primary hospitalization in the ICU. * Completeness of the medical record in terms of laboratory and instrumental studies and protocol of therapeutic and surgical treatment. Exclusion Criteria: * Refusal to participate in the study at any stage. * Death within one hour after hospitalization. * Missing data. * Patients who seek primary care 24 hours after injury. * Patients requiring transfer between profiles and hospitals for implementation of rehabilitation or other stages of therapy. * Patients with prematurely interrupted treatment. * Trauma combined with suffocation, drowning, frostbite, electrical trauma, or chemical and/or thermal burns. * Patients with pathological fractures. * Pregnant women. * Cases with predominantly severe craniocephalic (GCS \<7 points) or spinal injury (deep paresis and plegias).
Where this trial is running
Semey, Abai
- Emergency Hospital — Semey, Abai, Kazakhstan (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.