Developing a risk score for blood clots in cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a risk assessment model that identifies cancer-associated thrombosis patients who are at low and high risk for recurrent venous thromboembolism and clinically relevant bleeding within six months of diagnosis. It will involve the collection of blood samples for a biobank to support future research in cancer genetics and hemostasis. Participants will be followed up at three and six months post-enrollment to monitor for any bleeding events and changes in treatment. The study is expected to recruit participants over a two-year period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Objectively documented distal and/or proximal DVT of the limb (upper or lower extremity) and/or PE, splanchnic vein thrombosis and/or cerebral sinus vein thrombosis in presence of active cancer of all types
* Intended treatment of CAT for at least 6 months with parenteral or oral anticoagulants at therapeutic dosing.
* Estimated life expectancy \> 6 months
* Willingness to give an informed consent
* Age ≥ 18 years

Exclusion Criteria:

* Unusual site CAT (gonadal vein thrombosis, ovarian vein thrombosis, retinal vein thrombosis)
* Superficial vein thrombosis
* Refusal of informed consent \> 72 hrs of anticoagulants
* Age \< 18 years old

Where it's running

• Ottawa Hospital Research Institute
  Ottawa, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Marc Carrier, MD — Ottawa Hospital
• Study coordinator: Kristina Vrotniakaite-Bajerciene, MD
• Email: kvrotniakaite@toh.ca
• Phone: 613-737-8899

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.