Developing a liquid biopsy test for advanced prostate cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on creating the PRIME liquid biopsy test to analyze plasma samples from patients with metastatic prostate cancer. It aims to integrate various data types, including cell free DNA (cfDNA) mutations, structural genomic changes, and extracellular vesicle (EV) information. By employing advanced computational and sequencing techniques, the study seeks to enhance the diagnostic utility of liquid biopsies in clinical settings and trials for advanced prostate cancer. The goal is to provide a comprehensive evaluation of biomarkers that could inform treatment decisions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of prostate cancer
* Eligible for prostate cancer pharmacological treatment
* Given consent to study participation

Exclusion Criteria:

\- Histological diagnosis other than prostate cancer

Where it's running

• Istituto Romagnolo per lo Studio dei Tumori
  Meldola, Forlì-Cesena, Italy Recruiting
• Azienda Ospedaliera San Luigi
  Orbassano, Torino, Italy Recruiting
• Istituto Oncologico Veneto
  Padova, Italy Recruiting
• Santa Chiara Hospital
  Trento, Italy Recruiting

Study contacts

• Study coordinator: Orazio Caffo
• Email: orazio.caffo@apss.tn.it
• Phone: +39 0461902121

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.