Developing a library of samples from organ transplant patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a well-characterized library of blood, biopsy tissue, and urine samples from organ transplant recipients, as well as from healthy volunteers for comparison. The samples will be analyzed to understand how patients respond to transplant therapies and the immunosuppressive drugs used in transplantation. By studying these biological samples, researchers hope to tailor transplant therapies to individual patients, potentially reducing side effects. Participation involves donating samples, which will not affect the participants' treatment plans.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Recipients of or candidates for organ transplantation or organ donors for recipients under evaluation at Emory University or CHOA
* Normal volunteers to include individuals without any known end-stage organ disease who are not on any immunosuppressive medication, and individuals with conditions requiring immunosuppression (i.e. dermatological diseases) that do not require transplant therapies
* Ability to understand the purposes and risks of the study and willingly give written informed consent, or in the case of minors, ability to give minor assent (children older than 5 years of age), in conjunction with written guardian consent

Exclusion Criteria:

* Patients who fail to meet the criteria for transplantation or post-transplant follow-up by Emory or Children's Healthcare of Atlanta physicians
* Any condition that, in the opinion of the attending physician, would place the patient at undue risk by participating. Specific conditions include but are not limited to anemia prohibitive of phlebotomy, coagulopathy or technical considerations that would prevent acquisition of sufficient tissue on biopsy for clinical use, or medical urgency preventing timely administration of the consenting process.

Where it's running

• Children's Healthcare of Atlanta
  Atlanta, Georgia, United States Recruiting
• Emory University
  Atlanta, Georgia, United States Recruiting

Study contacts

• Principal investigator: Aneesh K Mehta, MD — Emory University
• Study coordinator: Shine Thomas, CRC
• Email: shine.thomas@emoryhealthcare.org
• Phone: 404-712-2004

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  Recruiting Universität Münster · Münster, North Rhine-Westphalia · NCT06652919

• Collection of biological materials from organ transplant patients

  This study is collecting samples from organ transplant patients to help researchers learn more about why transplants sometimes fail and to find better ways to detect rejection and other related issues.

  Recruiting Hospices Civils de Lyon · Lyon, Rhône · NCT04687865

• Improving long-term survival for organ transplant patients

  This study is testing ways to improve the long-term success of organ transplants by personalizing care and collecting samples from patients to better predict and prevent transplant rejection.

  Recruiting at 3 sites University Hospital, Limoges · Limoges and 3 other locations · NCT03997253

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.