Determining Vitamin D Needs in Different Ethnic Groups
Estimation of the Dietary Requirement for Vitamin D in Ethnic Groups: a Double-blind, Randomised, Dose-response Trial
This study is testing how much vitamin D3 different ethnic groups in the UK need during winter to stay healthy and strong.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 114 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Surrey Academic / other |
| Locations | 1 site (Guildford) |
| Trial ID | NCT06067477 on ClinicalTrials.gov |
What this trial studies
This study aims to conduct a double-blind, randomized, dose-response trial of vitamin D3 supplementation among UK adults of white European, South Asian, and black African/Caribbean ethnicities. Participants will be assigned to receive varying doses of vitamin D3 for 12 weeks, with the goal of identifying the dietary intake necessary to maintain adequate vitamin D levels during winter. The study will also assess the impact of supplementation on immune health, muscle strength, and overall well-being through blood tests and physical assessments.
Who should consider this trial
Good fit: Ideal candidates include British adults aged over 18 from white European, South Asian, or black African/Caribbean backgrounds living in England.
Not a fit: Patients with significant health issues or those on medications affecting vitamin D metabolism may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help establish tailored vitamin D intake recommendations for different ethnic groups, improving health outcomes related to vitamin D deficiency.
How similar studies have performed: Previous studies have indicated the importance of vitamin D in various populations, but this specific approach focusing on ethnic dietary requirements is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * British white European, black African/Caribbean, or South Asian (self-reported) * Living in England for \>2 months * Aged \>18 years * No significant health issues * English or Urdu speaker Exclusion Criteria: * Medical condition or history which might impact study measurements (e.g., ischaemic heart disease, type 1 and type 2 diabetes, thyroid disease, osteoporosis, haematological disease, malignancy) * Medications known to affect vitamin D metabolism (i.e., hormone replacement therapy, anti-oestrogens treatment, antiepileptic drugs, and breast cancer treatment) * Pregnant or planning pregnancy during the study period * Regular use of sun beds * Having a sun holiday one month prior to commencing study or plans for a sun holiday within the study period. A sun holiday is generally defined as a holiday in a sunny resort outside of the UK. The researchers will assess this on a case-by-case basis depending on the time of year and expected weather conditions * Reported participation in another clinical trial occurring simultaneously * Previous intolerance or allergic reaction to vitamin D
Where this trial is running
Guildford
- Faculty of Health and Medical Sciences — Guildford, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Abigail Bournot — University of Surrey
- Study coordinator: Abigail Bournot, PhD
- Email: a.bournot@surrey.ac.uk
- Phone: 01483689222
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.