Determining the right purge volume for blood sampling from PiccLines

The Right Amount of Purge Useful for Blood Sampling on PiccLine

Not applicable Interventional Rennes University Hospital · NCT05763186

This study tests the best amount of fluid to flush out PiccLines before taking blood samples to make sure the results are accurate for hospitalized patients.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment66 (estimated)
Ages18 Years and up
SexAll
SponsorRennes University Hospital Academic / other
Locations1 site (Rennes)
Trial IDNCT05763186 on ClinicalTrials.gov

What this trial studies

This study investigates the optimal volume of purge required for blood sampling from PiccLine systems, which are increasingly used for therapeutic and nutritional administration in patients. It aims to clarify the necessary purging process to prevent contamination of blood samples with infusion solutions, which can lead to inaccurate laboratory results. By focusing on hospitalized patients with newly placed PiccLines, the study seeks to establish evidence-based guidelines for blood collection practices in hematology. The interventions involve sampling and rinsing techniques to determine the most effective approach.

Who should consider this trial

Good fit: Ideal candidates are hospitalized adults aged 18 and older with a newly placed PiccLine in a clinical hematology unit.

Not a fit: Patients with severe anemia, those receiving parenteral nutrition, or individuals unable to undergo peripheral venous sampling will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of blood tests and reduce the need for repeat sampling in patients with PiccLines.

How similar studies have performed: While there is anecdotal evidence regarding purging volumes, this study represents a novel approach to systematically evaluate and establish best practices in blood sampling from PiccLines.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ≥ 18 years
2. Carrier of PiccLine one way polyurethane
3. Hospitalized in a clinical hematology unit This criterion minimises patient and practice heterogeneity.
4. PiccLine placement not older than 48 hours
5. Injection of at least one solution
6. Affiliated to a social security scheme
7. Having signed a free, informed and written consent

Exclusion Criteria:

1. Anemia below the transfusion threshold (hemoglobin level \< 7 g/dL) in relation to the patient's pathology
2. Parenteral nutrition
3. Peripheral venous sampling not possible (insufficient venous capital)
4. Protected person (adult subject to legal protection (safeguard of justice, curatorship, guardianship), person deprived of liberty, pregnant woman (declarative), breastfeeding woman and minor).

Where this trial is running

Rennes

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HematologyPiccLineblood collectionpurge
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.