Clinical trial Recruiting at 2 sites Observational Ages 18 to 60

Detecting kidney issues in people with obesity and metabolic health variations

Official title: Early Detection of Renal Abnormalities in Metabolically Healthy and Unhealthy Weight Excess"

Run by Istituto Auxologico Italiano · NCT06338631 · Data updated 2026-11-12

This study is trying to see if being obese and having metabolic issues affect kidney health in adults aged 18 to 60, while also testing how diet changes might help.

More Obesity trials

Quick facts

Study typeObservational
Ages18 Years to 60 Years
SexAll
Enrollment1000 (estimated)
SponsorIstituto Auxologico Italiano
Academic / other
Locations2 sites (Milan and 1 other locations)
StatusRecruiting
StartedAugust 1, 2023
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedAugust 3, 2025
Trial IDNCT06338631 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 60 with a BMI of 25 kg/m2 or higher.

Probably not a fit

Patients with diabetes, renal disease, or systemic autoimmune diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between obesity, metabolic syndrome, and renal health. It focuses on understanding whether obesity and metabolic alterations independently increase the risk of renal damage. Participants aged 18 to 60 with a BMI of at least 25 kg/m2 will be observed, with a particular emphasis on differentiating between metabolically healthy obese individuals and those with metabolic complications. The study will involve dietary interventions to assess their impact on renal function.

Why it matters

Potential benefit: If successful, this study could lead to tailored treatment strategies for obesity-related renal health issues.

How similar studies have gone: While the relationship between obesity and renal health has been studied, this specific approach focusing on metabolic phenotypes is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 18 and 60 years
* BMI at least 25 kg/m2

Exclusion Criteria:

* Pregnancy or breastfeeding
* Diabetes mellitus
* Renal disease
* Systemic autoimmune diseases with possible renal involvement
* Agonistic physical activity
* Heart failure
* Pharmacologcal treatment with RAAS-inhibitors, sartans, thiazide diuretics, loop diuretics
* Urinary tract infection

Where it's running

  • Istituto Auxologico Italiano, Città Studi ICANS
    Milan, Italy
    Recruiting
  • Programma Infradipartimentale di Dietoterapia nel Trapianto e nell' Insufficienza Renale Cronica, DAI di Medicina Interna ad Indirizzo Specialistico, del Policlinico Federico II di Napoli
    Naples, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.