Desarda versus Lichtenstein repair for primary inguinal hernia
Official title: Randomized Controlled Trial Comparing the Desarda Tissue Technique With the Lichtenstein Technique in Primary Inguinal Hernia Repair
Run by Consorci Sanitari de l'Alt Penedès i Garraf · NCT06650878 · Data updated 2026-11-12
This study will see if the Desarda (no-mesh) repair or the Lichtenstein (mesh) repair leads to fewer problems after surgery in adults with a primary unilateral inguinal hernia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 478 (estimated) |
| Sponsor | Consorci Sanitari de l'Alt Penedès i Garraf Academic / other |
| Locations | 1 site (Sant Pere de Ribes, Barcelona) |
| Status | Recruiting |
| Started | March 26, 2025 |
| Main results expected | December 1, 2028 |
| Study ends | December 1, 2031 |
| Registry record updated | October 27, 2026 |
| Trial ID | NCT06650878 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with a primary unilateral inguinal hernia, BMI under 31, suitable for an anterior (open) repair as outpatient or elective admission, and able to give informed consent.
✕Probably not a fit
Patients with a weak, thin, or divided external oblique aponeurosis, ongoing oncologic disease, cirrhosis Child B or worse, women with prior cesarean section, or those with cognitive/affective issues limiting cooperation are excluded and unlikely to benefit from this trial.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares two anterior surgical approaches for primary inguinal hernia repair: the non-mesh Desarda technique and the mesh-based Lichtenstein technique. Eligible adults with primary unilateral inguinal hernia and BMI below 31 who are scheduled for outpatient or elective anterior repair will undergo one of the two procedures at a single center. Participants will be followed for the occurrence of postoperative complications and other relevant outcomes. The trial is conducted at CSAPG in Sant Pere de Ribes, Barcelona, under the sponsorship of the local health consortium.
Why it matters
Potential benefit: If successful, the Desarda approach could reduce mesh-related problems and overall postoperative complications compared with the Lichtenstein repair.
How similar studies have gone: Previous series and meta-analyses have reported that Desarda repairs can achieve recurrence rates similar to mesh repairs with potentially less chronic pain, but results are mixed and not definitive.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed with primary inguinal hernia. * Body mass index below 31 * Indication for inguinal hernia repair via anterior approach, either as outpatient surgery (CMA) or elective admission. * Legal capacity to provide informed consent. Exclusion Criteria: * Patients with a weak, thin, or divided external oblique aponeurosis. * Participants diagnosed with any of the following conditions: * Ongoing oncological disease * Cirrhotic patients classified as Child B or higher * Women who have previously undergone a cesarean section * Cognitive or affective conditions that limit the ability to cooperate with the study procedures
Where it's running
-
Csapg
Sant Pere de Ribes, Barcelona, Spain Recruiting
Study contacts
- Principal investigator: Javier Errando, MD — Csapg
- Study coordinator: Javier Errando, MD
- Email: jerrando@csapg.cat
- Phone: +34938960025
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.